EC number:4.2.1.144

Enzyme

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     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.144
Description:3-amino-5-hydroxybenzoate synthase.
Alternative Name: AHBA synthase.
Cath: 3.40.640.10; 3.90.1150.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.144
BRENDA Enzyme Link: BRENDA 4.2.1.144
KEGG Enzyme Link: KEGG4.2.1.144
BioCyc Enzyme Link: BioCyc 4.2.1.144
ExPASy Enzyme Link: ExPASy4.2.1.144
EC2PDB Enzyme Link: EC2PDB 4.2.1.144
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.144
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.144
IntEnz Enzyme Link: IntEnz 4.2.1.144
MEDLINE Enzyme Link: MEDLINE 4.2.1.144

EC number:4.2.1.144

MSA:

4.2.1.144;
Phylogenetic Tree:

4.2.1.144;
Uniprot:
M-CSA:
RHEA:35771 5-deoxy-5-amino-3-dehydroshikimate = 3-amino-5-hydroxybenzoate + H(+) + H2O
RULE(radius=1) [*:1]-[CH;+0:2]1-[CH2;+0:3]-[C;H0;+0:4](-[*:5])=[CH;+0:6]-[C;H0;+0:7](=[O;H0;+0:8])-[CH;+0:9]-1-[OH;+0:10]>>[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[c;H0;+0:7](-[OH;+0:8]):[cH;+0:9]:1.[OH2;+0:10]
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References

TitleAuthorsDatePubMed ID
3-Amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.Kim CG, Yu TW, Fryhle CB, Handa S, Floss HG1998 Mar 139497318
Crystal structure of 3-amino-5-hydroxybenzoic acid (AHBA) synthase.Eads JC, Beeby M, Scapin G, Yu TW, Floss HG1999 Aug 310433690