EC number:4.2.1.164

Enzyme

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     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.164
Description:dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase.
Alternative Name: TDP-4-keto-2,6-dideoxy-D-glucose 3-dehydrase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.164
BRENDA Enzyme Link: BRENDA 4.2.1.164
KEGG Enzyme Link: KEGG4.2.1.164
BioCyc Enzyme Link: BioCyc 4.2.1.164
ExPASy Enzyme Link: ExPASy4.2.1.164
EC2PDB Enzyme Link: EC2PDB 4.2.1.164
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.164
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.164
IntEnz Enzyme Link: IntEnz 4.2.1.164
MEDLINE Enzyme Link: MEDLINE 4.2.1.164

EC number:4.2.1.164

MSA:

4.2.1.164;
Phylogenetic Tree:

4.2.1.164;
Uniprot:
M-CSA:
RHEA:49140 dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[Fe;H0;+0:6]-[*:7].[*:8]-[Fe;H0;+0:9]-[*:10].[H+;H0:11].[H+;H0:12]>>[*:1]-[CH2;+0:2]-[*:3].[*:5]-[Fe+;H0:6]-[*:7].[*:8]-[Fe+;H0:9]-[*:10].[OH2;+0:4]
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References

TitleAuthorsDatePubMed ID
In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa.Hong L, Zhao Z, Melançon CE 3rd, Zhang H, Liu HW2008 Apr 918345667
Characterization of SpnQ from the spinosyn biosynthetic pathway of Saccharopolyspora spinosa: mechanistic and evolutionary implications for C-3 deoxygenation in deoxysugar biosynthesis.Hong L, Zhao Z, Liu HW2006 Nov 817076492