EC number:4.2.1.77
| ID: | 4.2.1.77 |
|---|---|
| Description: | Trans-L-3-hydroxyproline dehydratase. |
| Cath: | 3.10.310.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.77 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.77 |
| KEGG Enzyme Link: | KEGG4.2.1.77 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.77 |
| ExPASy Enzyme Link: | ExPASy4.2.1.77 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.77 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.77 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.77 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.77 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.77 |
| RHEA:10320 | trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O |
| RULE(radius=1) | [*:1]-[CH;+0:2]1-[NH;+0:3]-[*:4]-[*:5]-[CH;+0:6]-1-[OH;+0:7]>>[*:1]-[C;H0;+0:2]1=[N;H0;+0:3]-[*:4]-[*:5]-[CH2;+0:6]-1.[OH2;+0:7] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A unique cis-3-hydroxy-l-proline dehydratase in the enolase superfamily. | Zhang X, Kumar R, Vetting MW, Zhao S, Jacobson MP, Almo SC, Gerlt JA | 2015 Feb 4 | 25608448 |
| Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks. | Zhao S, Sakai A, Zhang X, Vetting MW, Kumar R, Hillerich B, San Francisco B, Solbiati J, Steves A, Brown S, Akiva E, Barber A, Seidel RD, Babbitt PC, Almo SC, Gerlt JA, Jacobson MP | 2014 Jun 30 | 24980702 |
| Identification and characterization of trans-3-hydroxy-l-proline dehydratase and Δ(1)-pyrroline-2-carboxylate reductase involved in trans-3-hydroxy-l-proline metabolism of bacteria. | Watanabe S, Tanimoto Y, Yamauchi S, Tozawa Y, Sawayama S, Watanabe Y | 2014 | 24649405 |
| Identification of a human trans-3-hydroxy-L-proline dehydratase, the first characterized member of a novel family of proline racemase-like enzymes. | Visser WF, Verhoeven-Duif NM, de Koning TJ | 2012 Jun 22 | 22528483 |