EC number:4.2.1.94
| ID: | 4.2.1.94 |
|---|---|
| Description: | Scytalone dehydratase. |
| Cath: | 3.10.450.50; 3.40.50.720; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.94 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.94 |
| KEGG Enzyme Link: | KEGG4.2.1.94 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.94 |
| ExPASy Enzyme Link: | ExPASy4.2.1.94 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.94 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.94 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.94 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.94 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.94 |
| RHEA:24396 | scytalone = 1,3,8-trihydroxynaphthalene + H2O |
| RULE(radius=1) | [O;H0;+0:1]=[C;H0;+0:2]1-[*:3]:[*:4]-[CH2;+0:5]-[CH;+0:6](-[OH;+0:7])-[CH2;+0:8]-1>>[OH2;+0:7].[OH;+0:1]-[c;H0;+0:2]1:[*:3]:[*:4]:[cH;+0:5]:[cH;+0:6]:[cH;+0:8]:1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Role of a critical water in scytalone dehydratase-catalyzed reaction. | Zheng YJ, Bruice TC | 1998 Apr 14 | 9539706 |
| Roles of substrate distortion and intramolecular hydrogen bonding in enzymatic catalysis by scytalone dehydratase. | Zheng YJ, Basarab GS, Jordan DB | 2002 Jan 22 | 11790103 |
| Stereochemistry of the enolization of scytalone by scytalone dehydratase. | Jordan DB, Zheng YJ, Lockett BA, Basarab GS | 2000 Mar 7 | 10694394 |
| Catalytic mechanism of scytalone dehydratase: site-directed mutagenisis, kinetic isotope effects, and alternate substrates. | Basarab GS, Steffens JJ, Wawrzak Z, Schwartz RS, Lundqvist T, Jordan DB | 1999 May 11 | 10320327 |