| ID: | 4.2.3.131 |
|---|---|
| Description: | Miltiradiene synthase. |
| Cath: | 1.10.600.10; 1.50.10.130; 1.50.10.160; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 4.2.3.131 |
| BRENDA Enzyme Link: | BRENDA 4.2.3.131 |
| KEGG Enzyme Link: | KEGG4.2.3.131 |
| BioCyc Enzyme Link: | BioCyc 4.2.3.131 |
| ExPASy Enzyme Link: | ExPASy4.2.3.131 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.3.131 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.131 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.131 |
| IntEnz Enzyme Link: | IntEnz 4.2.3.131 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.3.131 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:33983 | (+)-copalyl diphosphate = diphosphate + miltiradiene |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[C;H0;+0:3](=[CH2;+0:4])-[CH;+0:5](-[*:6])-[CH2;+0:7]-[*:8]-[*:9](-[CH3;+0:10])=[*:11]-[CH2;+0:12]-[O;H0;+0:13]-[*:14]>>[*:1]-[CH2;+0:2]-[C;H0;+0:7]1=[C;H0;+0:5](-[*:6])-[CH2;+0:12]-[*:11]=[*:9](-[CH;+0:10](-[CH3;+0:3])-[CH3;+0:4])-[*:8]-1.[*:14]-[OH;+0:13] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of two genes for the biosynthesis of abietane-type diterpenes in rosemary (Rosmarinus officinalis) glandular trichomes. | Brückner K, Božić D, Manzano D, Papaefthimiou D, Pateraki I, Scheler U, Ferrer A, de Vos RC, Kanellis AK, Tissier A | 2014 May | 24569175 |
| A functional genomics approach to tanshinone biosynthesis provides stereochemical insights. | Gao W, Hillwig ML, Huang L, Cui G, Wang X, Kong J, Yang B, Peters RJ | 2009 Nov 19 | 19905026 |
| Enzymatic (13)C labeling and multidimensional NMR analysis of miltiradiene synthesized by bifunctional diterpene cyclase in Selaginella moellendorffii. | Sugai Y, Ueno Y, Hayashi K, Oogami S, Toyomasu T, Matsumoto S, Natsume M, Nozaki H, Kawaide H | 2011 Dec 16 | 22027823 |