EC number:4.2.3.132
| ID: | 4.2.3.132 |
|---|---|
| Description: | Neoabietadiene synthase. |
| Cath: | 1.10.600.10; 1.50.10.130; 1.50.10.160; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.3.132 |
| BRENDA Enzyme Link: | BRENDA 4.2.3.132 |
| KEGG Enzyme Link: | KEGG4.2.3.132 |
| BioCyc Enzyme Link: | BioCyc 4.2.3.132 |
| ExPASy Enzyme Link: | ExPASy4.2.3.132 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.3.132 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.132 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.132 |
| IntEnz Enzyme Link: | IntEnz 4.2.3.132 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.3.132 |
EC number:4.2.3.132
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:33987 | (+)-copalyl diphosphate = diphosphate + neoabietadiene |
| RULE(radius=1) | ([*:1]-[C;H0;+0:2](-[CH3;+0:3])=[CH;+0:4]-[CH2;+0:5]-[O;H0;+0:6]-[*:7].[*:8]=[CH2;+0:9])>>[*:1]-[C;H0;+0:2](-[CH;+0:9]=[*:8])=[C;H0;+0:4](-[CH3;+0:5])-[CH3;+0:3].[*:7]-[OH;+0:6] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Evolution of conifer diterpene synthases: diterpene resin acid biosynthesis in lodgepole pine and jack pine involves monofunctional and bifunctional diterpene synthases. | Hall DE, Zerbe P, Jancsik S, Quesada AL, Dullat H, Madilao LL, Yuen M, Bohlmann J | 2013 Feb | 23370714 |
| Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production. | Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R, Bohlmann J | 2012 Apr 6 | 22337889 |
| Abietadiene synthase from grand fir (Abies grandis): characterization and mechanism of action of the "pseudomature" recombinant enzyme. | Peters RJ, Flory JE, Jetter R, Ravn MM, Lee HJ, Coates RM, Croteau RB | 2000 Dec 19 | 11112547 |
| Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis. | Zhou K, Gao Y, Hoy JA, Mann FM, Honzatko RB, Peters RJ | 2012 Feb 24 | 22219188 |
| Diterpene resin acid biosynthesis in loblolly pine (Pinus taeda): functional characterization of abietadiene/levopimaradiene synthase (PtTPS-LAS) cDNA and subcellular targeting of PtTPS-LAS and abietadienol/abietadienal oxidase (PtAO, CYP720B1). | Ro DK, Bohlmann J | 2006 Aug | 16497345 |