EC number:4.2.3.190
| ID: | 4.2.3.190 |
|---|---|
| Description: | Manoyl oxide synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.3.190 |
| BRENDA Enzyme Link: | BRENDA 4.2.3.190 |
| KEGG Enzyme Link: | KEGG4.2.3.190 |
| BioCyc Enzyme Link: | BioCyc 4.2.3.190 |
| ExPASy Enzyme Link: | ExPASy4.2.3.190 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.3.190 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.190 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.190 |
| IntEnz Enzyme Link: | IntEnz 4.2.3.190 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.3.190 |
EC number:4.2.3.190
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:54516 | 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate |
| RULE(radius=1) | ([*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[CH2;+0:5]-[O;H0;+0:6]-[*:7].[*:8]-[OH;+0:9])>>[*:1]-[C;H0;+0:2](-[*:3])(-[CH;+0:4]=[CH2;+0:5])-[O;H0;+0:9]-[*:8].[*:7]-[OH;+0:6] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Diterpene synthases of the biosynthetic system of medicinally active diterpenoids in Marrubium vulgare. | Zerbe P, Chiang A, Dullat H, O'Neil-Johnson M, Starks C, Hamberger B, Bohlmann J | 2014 Sep | 24990389 |
| Manoyl oxide (13R), the biosynthetic precursor of forskolin, is synthesized in specialized root cork cells in Coleus forskohlii. | Pateraki I, Andersen-Ranberg J, Hamberger B, Heskes AM, Martens HJ, Zerbe P, Bach SS, Møller BL, Bohlmann J, Hamberger B | 2014 Mar | 24481136 |
| Gene discovery of modular diterpene metabolism in nonmodel systems. | Zerbe P, Hamberger B, Yuen MM, Chiang A, Sandhu HK, Madilao LL, Nguyen A, Hamberger B, Bach SS, Bohlmann J | 2013 Jun | 23613273 |