EC number:5.5.1.4

Enzyme

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     5. Isomerases
        5.5 Intramolecular lyases
            5.5.1 Intramolecular lyases (only sub-subclass identified to date)
ID:5.5.1.4
Description:Inositol-3-phosphate synthase.
Alternative Name: Myo-inositol-1-phosphate synthase.
Inositol 1-phosphate synthetase.
Glucose 6-phosphate cyclase.
Glucocycloaldolase.
D-glucose 6-phosphate cycloaldolase.
1L-myo-inositol-1-phosphate lyase (isomerizing).
Cath: 3.30.2360.10; 3.30.360.10; 3.40.50.720; 3.40.50.1480;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 5.5.1.4
BRENDA Enzyme Link: BRENDA 5.5.1.4
KEGG Enzyme Link: KEGG5.5.1.4
BioCyc Enzyme Link: BioCyc 5.5.1.4
ExPASy Enzyme Link: ExPASy5.5.1.4
EC2PDB Enzyme Link: EC2PDB 5.5.1.4
ExplorEnz Enzyme Link: ExplorEnz 5.5.1.4
PRIAM enzyme-specific profiles Link: PRIAM 5.5.1.4
IntEnz Enzyme Link: IntEnz 5.5.1.4
MEDLINE Enzyme Link: MEDLINE 5.5.1.4

EC number:5.5.1.4

MSA:

5.5.1.4;
Phylogenetic Tree:

5.5.1.4;
Uniprot:
M-CSA:
RHEA:10716 D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[*:5]-[CH2;+0:6]-[*:7]>>[*:1]-[CH;+0:2](-[*:3])-[CH;+0:6](-[*:7])-[*:5]-[OH;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
The Arabidopsis thaliana Myo-inositol 1-phosphate synthase1 gene is required for Myo-inositol synthesis and suppression of cell death.Donahue JL, Alford SR, Torabinejad J, Kerwin RE, Nourbakhsh A, Ray WK, Hernick M, Huang X, Lyons BM, Hein PP, Gillaspy GE2010 Mar20215587
Human 1-D-myo-inositol-3-phosphate synthase is functional in yeast.Ju S, Shaltiel G, Shamir A, Agam G, Greenberg ML2004 May 2115024000
Molecular characterization of Drosophila melanogaster myo-inositol-1-phosphate synthase.Park D, Jeong S, Lee S, Park S, Kim JI, Yim J2000 Dec 111121586