FAQ: BioSynther

One of the most promising applications of biosynthetic methods is to produce chemical products of high value from the ready-made chemicals. To explore the biosynthetic potentials of a chemical as a synthesis precursor, biosynthetic database and related informatics tools are urgently needed. In the present work, a web-based tool, BioSynther, is developed to explore the biosynthetic potentials of precursor chemicals using BKM-react, Rhea, and more than 50,000 in-house RxnFinder reactions manually curated from about 120 thousand literature. BioSynther allows researchers to explore biosynthetic potentials step by step interactively, which could be used as a useful tool in metabolic engineering.