Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.100
Description:3-oxoacyl-[acyl-carrier-protein] reductase.
Prosite: PDOC00060;
PDB:
PDBScop
Cath: 1.10.110.40; 1.10.1200.10; 1.10.1470.20; 1.10.287.1960; 1.10.287.3140; 1.10.287.3150; 1.20.1050.120; 1.20.5.3540; 1.20.5.3640; 3.20.20.70;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.100
BRENDA Enzyme Link: BRENDA 1.1.1.100
KEGG Enzyme Link: KEGG1.1.1.100
BioCyc Enzyme Link: BioCyc 1.1.1.100
ExPASy Enzyme Link: ExPASy1.1.1.100
EC2PDB Enzyme Link: EC2PDB 1.1.1.100
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.100
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.100
IntEnz Enzyme Link: IntEnz 1.1.1.100
MEDLINE Enzyme Link: MEDLINE 1.1.1.100
MSA:

1.1.1.100;

Phylogenetic Tree:

1.1.1.100;

Uniprot:
M-CSA:
RHEA:17397 a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Acyl carrier protein.Prescott DJ, Vagelos PR19724561013
Studies on the mechanism of fatty acid synthesis. XV. Preparation and general properties of beta-ketoacyl acyl carrier protein reductase from Escherichia coli.Toomey RE, Wakil SJ1966 Apr 44381013
Purification and characterizations of beta-Ketoacyl-[acyl-carrier-protein] reductase, beta-hydroxyacyl-[acyl-carrier-protein] dehydrase, and enoyl-[acyl-carrier-protein] reductase from Spinacia oleracea leaves.Shimakata T, Stumpf PK1982 Oct 16756317