EC number:1.1.1.118

Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.118
Description:Glucose 1-dehydrogenase (NAD(+)).
Cath: 3.40.50.720; 3.90.180.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.118
BRENDA Enzyme Link: BRENDA 1.1.1.118
KEGG Enzyme Link: KEGG1.1.1.118
BioCyc Enzyme Link: BioCyc 1.1.1.118
ExPASy Enzyme Link: ExPASy1.1.1.118
EC2PDB Enzyme Link: EC2PDB 1.1.1.118
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.118
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.118
IntEnz Enzyme Link: IntEnz 1.1.1.118
MEDLINE Enzyme Link: MEDLINE 1.1.1.118

EC number:1.1.1.118

MSA:

1.1.1.118;
Phylogenetic Tree:

1.1.1.118;
Uniprot:
M-CSA:
RHEA:14293 D-glucose + NAD(+) = D-glucono-1,5-lactone + H(+) + NADH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Carbohydrate metabolism in Thermoproteus tenax: in vivo utilization of the non-phosphorylative Entner-Doudoroff pathway and characterization of its first enzyme, glucose dehydrogenase.Siebers B, Wendisch VF, Hensel R1997 Aug9238103
Glucose dehydrogenase from the halophilic Archaeon Haloferax mediterranei: enzyme purification, characterisation and N-terminal sequence.Bonete MJ, Pire C, LLorca FI, Camacho ML1996 Apr 18925901
Cloning, sequencing and expression of the gene encoding glucose dehydrogenase from the thermophilic archaeon Thermoplasma acidophilum.Bright JR, Byrom D, Danson MJ, Hough DW, Towner P1993 Feb 18436115
Glucose dehydrogenase from the thermoacidophilic archaebacterium Sulfolobus solfataricus.Giardina P, de Biasi MG, de Rosa M, Gambacorta A, Buonocore V1986 Nov 13827812
Purification and characterization of glucose dehydrogenase from the thermoacidophilic archaebacterium Thermoplasma acidophilum.Smith LD, Budgen N, Bungard SJ, Danson MJ, Hough DW1989 Aug 12803257
Metabolic pathway promiscuity in the archaeon Sulfolobus solfataricus revealed by studies on glucose dehydrogenase and 2-keto-3-deoxygluconate aldolase.Lamble HJ, Heyer NI, Bull SD, Hough DW, Danson MJ2003 Sep 512824170
Heterologous overexpression of glucose dehydrogenase from the halophilic archaeon Haloferax mediterranei, an enzyme of the medium chain dehydrogenase/reductase family.Pire C, Esclapez J, Ferrer J, Bonete MJ2001 Jun 2511425479