EC number:1.1.1.119

Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.119
Description:Glucose 1-dehydrogenase (NADP(+)).
Cath: 3.40.50.720; 3.90.180.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.119
BRENDA Enzyme Link: BRENDA 1.1.1.119
KEGG Enzyme Link: KEGG1.1.1.119
BioCyc Enzyme Link: BioCyc 1.1.1.119
ExPASy Enzyme Link: ExPASy1.1.1.119
EC2PDB Enzyme Link: EC2PDB 1.1.1.119
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.119
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.119
IntEnz Enzyme Link: IntEnz 1.1.1.119
MEDLINE Enzyme Link: MEDLINE 1.1.1.119

EC number:1.1.1.119

MSA:

1.1.1.119;
Phylogenetic Tree:

1.1.1.119;
Uniprot:
M-CSA:
RHEA:14405 D-glucose + NADP(+) = D-glucono-1,5-lactone + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Carbohydrate metabolism in Thermoproteus tenax: in vivo utilization of the non-phosphorylative Entner-Doudoroff pathway and characterization of its first enzyme, glucose dehydrogenase.Siebers B, Wendisch VF, Hensel R1997 Aug9238103
Glucose dehydrogenase from the halophilic Archaeon Haloferax mediterranei: enzyme purification, characterisation and N-terminal sequence.Bonete MJ, Pire C, LLorca FI, Camacho ML1996 Apr 18925901
Cloning, sequencing and expression of the gene encoding glucose dehydrogenase from the thermophilic archaeon Thermoplasma acidophilum.Bright JR, Byrom D, Danson MJ, Hough DW, Towner P1993 Feb 18436115
Glucose dehydrogenase from the thermoacidophilic archaebacterium Sulfolobus solfataricus.Giardina P, de Biasi MG, de Rosa M, Gambacorta A, Buonocore V1986 Nov 13827812
Purification and characterization of glucose dehydrogenase from the thermoacidophilic archaebacterium Thermoplasma acidophilum.Smith LD, Budgen N, Bungard SJ, Danson MJ, Hough DW1989 Aug 12803257
The structural basis of substrate promiscuity in glucose dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus.Milburn CC, Lamble HJ, Theodossis A, Bull SD, Hough DW, Danson MJ, Taylor GL2006 May 2616556607
Properties of the recombinant glucose/galactose dehydrogenase from the extreme thermoacidophile, Picrophilus torridus.Angelov A, Fütterer O, Valerius O, Braus GH, Liebl W2005 Feb15691337
Metabolic pathway promiscuity in the archaeon Sulfolobus solfataricus revealed by studies on glucose dehydrogenase and 2-keto-3-deoxygluconate aldolase.Lamble HJ, Heyer NI, Bull SD, Hough DW, Danson MJ2003 Sep 512824170
Heterologous overexpression of glucose dehydrogenase from the halophilic archaeon Haloferax mediterranei, an enzyme of the medium chain dehydrogenase/reductase family.Pire C, Esclapez J, Ferrer J, Bonete MJ2001 Jun 2511425479