EC number:1.1.1.127

Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.127
Description:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase.
Alternative Name: 2-keto-3-deoxygluconate dehydrogenase.
Cath: 3.40.50.720;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.127
BRENDA Enzyme Link: BRENDA 1.1.1.127
KEGG Enzyme Link: KEGG1.1.1.127
BioCyc Enzyme Link: BioCyc 1.1.1.127
ExPASy Enzyme Link: ExPASy1.1.1.127
EC2PDB Enzyme Link: EC2PDB 1.1.1.127
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.127
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.127
IntEnz Enzyme Link: IntEnz 1.1.1.127
MEDLINE Enzyme Link: MEDLINE 1.1.1.127

EC number:1.1.1.127

MSA:

1.1.1.127;
Phylogenetic Tree:

1.1.1.127;
Uniprot:
M-CSA:
RHEA:24232 2-dehydro-3-deoxy-D-gluconate + NAD(+) = 3-deoxy-D-glycero-2,5-hexodiulosonate + H(+) + NADH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Escherichia coli kduD encodes an oxidoreductase that converts both sugar and steroid substrates.Tubeleviciute A, Teese MG, Jose J2014 Jun24509771
Analysis of an Erwinia chrysanthemi gene cluster involved in pectin degradation.Condemine G, Robert-Baudouy J1991 Sep1766386
Polygalacturonic acid metabolism in bacteria. II. Formation and metabolism of 3-deoxy-D-glycero-2, 5-hexodiulosonic acid.PREISS J, ASHWELL G1963 May13986017