EC number:1.1.1.136

Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.136
Description:UDP-N-acetylglucosamine 6-dehydrogenase.
Alternative Name: UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.136
BRENDA Enzyme Link: BRENDA 1.1.1.136
KEGG Enzyme Link: KEGG1.1.1.136
BioCyc Enzyme Link: BioCyc 1.1.1.136
ExPASy Enzyme Link: ExPASy1.1.1.136
EC2PDB Enzyme Link: EC2PDB 1.1.1.136
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.136
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.136
IntEnz Enzyme Link: IntEnz 1.1.1.136
MEDLINE Enzyme Link: MEDLINE 1.1.1.136

EC number:1.1.1.136

MSA:

1.1.1.136;
Phylogenetic Tree:

1.1.1.136;
Uniprot:
M-CSA:
RHEA:13325 H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = 3 H(+) + 2 NADH + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]-[c;H0;+0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[n+;H0:9](-[*:10]):[cH;+0:11]:1.[*:12]-[n+;H0:13]1:[cH;+0:14]:[cH;+0:15]:[cH;+0:16]:[c;H0;+0:17](-[*:18]):[cH;+0:19]:1.[OH2;+0:20]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:20].[*:4]-[C;H0;+0:5]1=[CH;+0:11]-[N;H0;+0:9](-[*:10])-[CH;+0:8]=[CH;+0:7]-[CH2;+0:6]-1.[*:12]-[N;H0;+0:13]1-[CH;+0:14]=[CH;+0:15]-[CH2;+0:16]-[C;H0;+0:17](-[*:18])=[CH;+0:19]-1
Reaction
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References

TitleAuthorsDatePubMed ID
UDPacetylglucosamine dehydrogenase from Achromobacter georgiopolitanum.Fan DF, John CE, Zalitis J, Feingold DS1969 Dec4312076
Biochemical characterization of WbpA, a UDP-N-acetyl-D-glucosamine 6-dehydrogenase involved in O-antigen biosynthesis in Pseudomonas aeruginosa PAO1.Miller WL, Wenzel CQ, Daniels C, Larocque S, Brisson JR, Lam JS2004 Sep 315226302