EC number:1.1.1.154
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.154 |
|---|---|
| Description: | Ureidoglycolate dehydrogenase. |
| Cath: | 1.10.1530.10; 3.30.1370.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.154 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.154 |
| KEGG Enzyme Link: | KEGG1.1.1.154 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.154 |
| ExPASy Enzyme Link: | ExPASy1.1.1.154 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.154 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.154 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.154 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.154 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.154 |
EC number:1.1.1.154
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:15333 | (S)-ureidoglycolate + NADP(+) = H(+) + N-carbamoyl-2-oxoglycine + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| S-ureidoglycolate dehydrogenase: purification and properties. | van der Drift C, van Helvoort PE, Vogels GD | 1971 Aug | 4399430 |
| RHEA:15329 | (S)-ureidoglycolate + NAD(+) = H(+) + N-carbamoyl-2-oxoglycine + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| S-ureidoglycolate dehydrogenase: purification and properties. | van der Drift C, van Helvoort PE, Vogels GD | 1971 Aug | 4399430 |
| Structural and functional insights into (S)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization. | Kim MI, Shin I, Cho S, Lee J, Rhee S | 2012 | 23284870 |