| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.156 |
|---|---|
| Description: | Glycerol 2-dehydrogenase (NADP(+)). |
| Alternative Name: |
Dihydroxyacetone reductase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.1.1.156 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.156 |
| KEGG Enzyme Link: | KEGG1.1.1.156 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.156 |
| ExPASy Enzyme Link: | ExPASy1.1.1.156 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.156 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.156 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.156 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.156 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.156 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:12753 | glycerol + NADP(+) = dihydroxyacetone + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| NADP specific dihydroxyacetone reductase from Dunaliella parva. | Ben-Amotz A, Avron M | 1973 Jan 15 | 4146296 |
| Development of a bioconversion system using Saccharomyces cerevisiae Reductase YOR120W and Bacillus subtilis glucose dehydrogenase for chiral alcohol synthesis. | Yoon SA, Kim HK | 2013 Oct 28 | 23770562 |
| Functional studies of aldo-keto reductases in Saccharomyces cerevisiae. | Chang Q, Griest TA, Harter TM, Petrash JM | 2007 Mar | 17140678 |
| Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina. | Liepins J, Kuorelahti S, Penttilä M, Richard P | 2006 Sep | 16930134 |
| Functional genomic studies of aldo-keto reductases. | Petrash JM, Murthy BS, Young M, Morris K, Rikimaru L, Griest TA, Harter T | 2001 Jan 30 | 11306085 |
| Crystallization and aldo-keto reductase activity of Gcy1p from Saccharomyces cerevisiae. | Hur E, Wilson DK | 2000 Jun | 10818358 |