Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.156
Description:Glycerol 2-dehydrogenase (NADP(+)).
Alternative Name: Dihydroxyacetone reductase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.156
BRENDA Enzyme Link: BRENDA 1.1.1.156
KEGG Enzyme Link: KEGG1.1.1.156
BioCyc Enzyme Link: BioCyc 1.1.1.156
ExPASy Enzyme Link: ExPASy1.1.1.156
EC2PDB Enzyme Link: EC2PDB 1.1.1.156
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.156
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.156
IntEnz Enzyme Link: IntEnz 1.1.1.156
MEDLINE Enzyme Link: MEDLINE 1.1.1.156
MSA:

1.1.1.156;

Phylogenetic Tree:

1.1.1.156;

Uniprot:
M-CSA:
RHEA:12753 glycerol + NADP(+) = dihydroxyacetone + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
NADP specific dihydroxyacetone reductase from Dunaliella parva.Ben-Amotz A, Avron M1973 Jan 154146296
Development of a bioconversion system using Saccharomyces cerevisiae Reductase YOR120W and Bacillus subtilis glucose dehydrogenase for chiral alcohol synthesis.Yoon SA, Kim HK2013 Oct 2823770562
Functional studies of aldo-keto reductases in Saccharomyces cerevisiae.Chang Q, Griest TA, Harter TM, Petrash JM2007 Mar17140678
Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina.Liepins J, Kuorelahti S, Penttilä M, Richard P2006 Sep16930134
Functional genomic studies of aldo-keto reductases.Petrash JM, Murthy BS, Young M, Morris K, Rikimaru L, Griest TA, Harter T2001 Jan 3011306085
Crystallization and aldo-keto reductase activity of Gcy1p from Saccharomyces cerevisiae.Hur E, Wilson DK2000 Jun10818358