Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.184
Description:Carbonyl reductase (NADPH).
Alternative Name: Xenobiotic ketone reductase.
Prostaglandin 9-ketoreductase.
NADPH-dependent carbonyl reductase.
Aldehyde reductase I.
Prosite: PDOC00060;
PDB:
PDBScop
Cath: 3.40.50.720;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.184
BRENDA Enzyme Link: BRENDA 1.1.1.184
KEGG Enzyme Link: KEGG1.1.1.184
BioCyc Enzyme Link: BioCyc 1.1.1.184
ExPASy Enzyme Link: ExPASy1.1.1.184
EC2PDB Enzyme Link: EC2PDB 1.1.1.184
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.184
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.184
IntEnz Enzyme Link: IntEnz 1.1.1.184
MEDLINE Enzyme Link: MEDLINE 1.1.1.184
MSA:

1.1.1.184;

Phylogenetic Tree:

1.1.1.184;

Uniprot:
M-CSA:
RHEA:19257 a secondary alcohol + NADP(+) = a ketone + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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