EC number:1.1.1.202
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.202 | ||
|---|---|---|---|
| Description: | 1,3-propanediol dehydrogenase. | ||
| Alternative Name: |
3-hydroxypropionaldehyde reductase. 1,3-propanediol oxidoreductase. | ||
| Prosite: | PDOC00059; | ||
| PDB: |
|
||
| Cath: | 1.20.1090.10; 3.40.50.1970; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.202 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.202 |
| KEGG Enzyme Link: | KEGG1.1.1.202 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.202 |
| ExPASy Enzyme Link: | ExPASy1.1.1.202 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.202 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.202 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.202 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.202 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.202 |
EC number:1.1.1.202
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:23188 | NAD(+) + propane-1,3-diol = 3-hydroxypropanal + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[OH;+0:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Glycerol conversion to 1,3-propanediol by Clostridium pasteurianum: cloning and expression of the gene encoding 1,3-propanediol dehydrogenase. | Luers F, Seyfried M, Daniel R, Gottschalk G | 1997 Sep 15 | 9311132 |
| Purification of 1,3-propanediol dehydrogenase from Citrobacter freundii and cloning, sequencing, and overexpression of the corresponding gene in Escherichia coli. | Daniel R, Boenigk R, Gottschalk G | 1995 Apr | 7721705 |
| 1,3-Propanediol dehydrogenase from Klebsiella pneumoniae: decameric quaternary structure and possible subunit cooperativity. | Marçal D, Rêgo AT, Carrondo MA, Enguita FJ | 2009 Feb | 19011020 |