EC number:1.1.1.211
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.211 |
|---|---|
| Description: | Long-chain-3-hydroxyacyl-CoA dehydrogenase. |
| Alternative Name: |
Beta-hydroxyacyl-CoA dehydrogenase. |
| Cath: | 1.10.1040.10; 1.10.1040.50; 1.20.5.2720; 1.20.5.30; 1.20.5.3020; 3.40.50.720; 3.90.226.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.211 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.211 |
| KEGG Enzyme Link: | KEGG1.1.1.211 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.211 |
| ExPASy Enzyme Link: | ExPASy1.1.1.211 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.211 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.211 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.211 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.211 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.211 |
EC number:1.1.1.211
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:52656 | a long-chain (3S)-hydroxy fatty acyl-CoA + NAD(+) = a long-chain 3-oxo-fatty acyl-CoA + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[n+;H0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[C;H0;+0:6]1=[CH;+0:12]-[N;H0;+0:10](-[*:11])-[CH;+0:9]=[CH;+0:8]-[CH2;+0:7]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| beta-Oxidation enzymes in fibroblasts from patients with 3-hydroxydicarboxylic aciduria. | Venizelos N, Ijlst L, Wanders RJ, Hagenfeldt L | 1994 Jul | 7936829 |
| The molecular basis of pediatric long chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with maternal acute fatty liver of pregnancy. | Sims HF, Brackett JC, Powell CK, Treem WR, Hale DE, Bennett MJ, Gibson B, Shapiro S, Strauss AW | 1995 Jan 31 | 7846063 |
| The existence of an inner-membrane-bound, long acyl-chain-specific 3-hydroxyacyl-CoA dehydrogenase in mammalian mitochondria. | El-Fakhri M, Middleton B | 1982 Nov 12 | 7150615 |