EC number:1.1.1.22
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.22 |
|---|---|
| Description: | UDP-glucose 6-dehydrogenase. |
| Cath: | 1.10.1040.10; 1.20.5.10; 1.20.5.100; 3.40.50.720; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.22 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.22 |
| KEGG Enzyme Link: | KEGG1.1.1.22 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.22 |
| ExPASy Enzyme Link: | ExPASy1.1.1.22 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.22 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.22 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.22 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.22 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.22 |
| RHEA:23596 | H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]-[c;H0;+0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[n+;H0:9](-[*:10]):[cH;+0:11]:1.[*:12]-[n+;H0:13]1:[cH;+0:14]:[cH;+0:15]:[cH;+0:16]:[c;H0;+0:17](-[*:18]):[cH;+0:19]:1.[OH2;+0:20]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:20].[*:4]-[C;H0;+0:5]1=[CH;+0:11]-[N;H0;+0:9](-[*:10])-[CH;+0:8]=[CH;+0:7]-[CH2;+0:6]-1.[*:12]-[N;H0;+0:13]1-[CH;+0:14]=[CH;+0:15]-[CH2;+0:16]-[C;H0;+0:17](-[*:18])=[CH;+0:19]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Molecular cloning and characterization of the human and mouse UDP-glucose dehydrogenase genes. | Spicer AP, Kaback LA, Smith TJ, Seldin MF | 1998 Sep 25 | 9737970 |