EC number:1.1.1.233

Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.233
Description:N-acylmannosamine 1-dehydrogenase.
Alternative Name: N-acylmannosamine dehydrogenase.
N-acyl-D-mannosamine dehydrogenase.
N-acetyl-D-mannosamine dehydrogenase.
Prosite: PDOC00060;
PDB:
PDBScop
Cath: 3.40.50.720;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.233
BRENDA Enzyme Link: BRENDA 1.1.1.233
KEGG Enzyme Link: KEGG1.1.1.233
BioCyc Enzyme Link: BioCyc 1.1.1.233
ExPASy Enzyme Link: ExPASy1.1.1.233
EC2PDB Enzyme Link: EC2PDB 1.1.1.233
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.233
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.233
IntEnz Enzyme Link: IntEnz 1.1.1.233
MEDLINE Enzyme Link: MEDLINE 1.1.1.233

EC number:1.1.1.233

MSA:

1.1.1.233;
Phylogenetic Tree:

1.1.1.233;
Uniprot:
M-CSA:
RHEA:11540 an N-acyl-D-mannosamine + NAD(+) = an N-acyl-D-mannosaminolactone + H(+) + NADH
RULE(radius=1) ([*:1]-[CH;+0:2]=[*:3].[*:4]-[OH;+0:5]).[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:5]-[*:4].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Purification and properties of N-acyl-D-mannosamine dehydrogenase from Flavobacterium sp. 141-8.Horiuchi T, Kurokawa T1988 Sep3240988
Crystal structures and functional studies clarify substrate selectivity and catalytic residues for the unique orphan enzyme N-acetyl-D-mannosamine dehydrogenase.Sola-Carvajal A, Gil-Ortiz F, García-Carmona F, Rubio V, Sánchez-Ferrer Á2014 Sep 1524969681
Cloning, sequencing, and expression of the N-acyl-D-mannosamine dehydrogenase gene from Flavobacterium sp. strain 141-8 in Escherichia coli.Yamamoto-Otake H, Koyama Y, Horiuchi T, Nakano E1991 May1854199