Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.244
Description:Methanol dehydrogenase.
Prosite: PDOC00059;
PDB:
PDBScop

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.244
BRENDA Enzyme Link: BRENDA 1.1.1.244
KEGG Enzyme Link: KEGG1.1.1.244
BioCyc Enzyme Link: BioCyc 1.1.1.244
ExPASy Enzyme Link: ExPASy1.1.1.244
EC2PDB Enzyme Link: EC2PDB 1.1.1.244
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.244
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.244
IntEnz Enzyme Link: IntEnz 1.1.1.244
MEDLINE Enzyme Link: MEDLINE 1.1.1.244
MSA:

1.1.1.244;

Phylogenetic Tree:

1.1.1.244;

Uniprot:
M-CSA:
RHEA:19401 methanol + NAD(+) = formaldehyde + H(+) + NADH
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[CH3;+0:9]-[OH;+0:10]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[CH2;+0:9]=[O;H0;+0:10]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Properties of an NAD(H)-containing methanol dehydrogenase and its activator protein from Bacillus methanolicus.Arfman N, Hektor HJ, Bystrykh LV, Govorukhina NI, Dijkhuizen L, Frank J1997 Mar 19119008
Methanol metabolism in thermotolerant methylotrophic Bacillus strains involving a novel catabolic NAD-dependent methanol dehydrogenase as a key enzyme.Arfman N, Watling EM, Clement W, van Oosterwijk RJ, de Vries GE, Harder W, Attwood MM, Dijkhuizen L19892673121
Purification and characterization of an activator protein for methanol dehydrogenase from thermotolerant Bacillus spp.Arfman N, Van Beeumen J, De Vries GE, Harder W, Dijkhuizen L1991 Feb 251995643
Identification of a magnesium-dependent NAD(P)(H)-binding domain in the nicotinoprotein methanol dehydrogenase from Bacillus methanolicus.Hektor HJ, Kloosterman H, Dijkhuizen L2002 Dec 612351635
Molecular, biochemical, and functional characterization of a Nudix hydrolase protein that stimulates the activity of a nicotinoprotein alcohol dehydrogenase.Kloosterman H, Vrijbloed JW, Dijkhuizen L2002 Sep 2012089158