EC number:1.1.1.268
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.268 |
|---|---|
| Description: | 2-(R)-hydroxypropyl-CoM dehydrogenase. |
| Alternative Name: |
2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase. |
| Cath: | 3.30.390.30; 3.40.50.720; 3.50.50.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.268 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.268 |
| KEGG Enzyme Link: | KEGG1.1.1.268 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.268 |
| ExPASy Enzyme Link: | ExPASy1.1.1.268 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.268 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.268 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.268 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.268 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.268 |
EC number:1.1.1.268
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:13249 | (R)-2-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Aliphatic epoxide carboxylation. | Ensign SA, Allen JR | 2003 | 12524213 |
| A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation. | Allen JR, Clark DD, Krum JG, Ensign SA | 1999 Jul 20 | 10411892 |