EC number:1.1.1.28
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.28 | ||
|---|---|---|---|
| Description: | D-lactate dehydrogenase. | ||
| Alternative Name: |
D-lactic dehydrogenase. D-lactic acid dehydrogenase. | ||
| Prosite: | PDOC00063; | ||
| PDB: |
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| Cath: | 3.30.1370.20; 3.30.43.10; 3.30.465.10; 3.30.70.610; 3.40.50.720; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.28 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.28 |
| KEGG Enzyme Link: | KEGG1.1.1.28 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.28 |
| ExPASy Enzyme Link: | ExPASy1.1.1.28 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.28 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.28 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.28 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.28 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.28 |
| RHEA:16369 | (R)-lactate + NAD(+) = H(+) + NADH + pyruvate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Chemical characterization of D-lactate dehydrogenase from Escherichia coli B. | Tarmy EM, Kaplan NO | 1968 May 25 | 4297265 |
| Diverse allosteric and catalytic functions of tetrameric d-lactate dehydrogenases from three Gram-negative bacteria. | Furukawa N, Miyanaga A, Togawa M, Nakajima M, Taguchi H | 2014 | 25401076 |
| D- and L-lactic acid dehydrogenases in Lactobacillus plantarum. | DENNIS D, KAPLAN NO | 1960 Mar | 13815938 |