EC number:1.1.1.29
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.29 | ||
|---|---|---|---|
| Description: | Glycerate dehydrogenase. | ||
| Alternative Name: |
Hydroxypyruvate dehydrogenase. D-glycerate dehydrogenase. | ||
| Prosite: | PDOC00063; | ||
| PDB: |
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| Cath: | 3.40.50.720; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.29 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.29 |
| KEGG Enzyme Link: | KEGG1.1.1.29 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.29 |
| ExPASy Enzyme Link: | ExPASy1.1.1.29 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.29 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.29 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.29 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.29 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.29 |
| RHEA:17905 | D-glycerate + NAD(+) = 3-hydroxypyruvate + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of a NAD-dependent D-glycerate dehydrogenase at 2.4 A resolution. | Goldberg JD, Yoshida T, Brick P | 1994 Mar 4 | 8120891 |
| Purification and characterization of hydroxypyruvate reductase from a serine-producing methylotroph, Hyphomicrobium methylovorum GM2. | Izumi Y, Yoshida T, Kanzaki H, Toki S, Miyazaki SS, Yamada H | 1990 Jun 20 | 2114287 |
| Shoot-specific down-regulation of protein farnesyltransferase (alpha-subunit) for yield protection against drought in canola. | Wang Y, Beaith M, Chalifoux M, Ying J, Uchacz T, Sarvas C, Griffiths R, Kuzma M, Wan J, Huang Y | 2009 Jan | 19529821 |
| A cytosolic pathway for the conversion of hydroxypyruvate to glycerate during photorespiration in Arabidopsis. | Timm S, Nunes-Nesi A, Pärnik T, Morgenthal K, Wienkoop S, Keerberg O, Weckwerth W, Kleczkowski LA, Fernie AR, Bauwe H | 2008 Oct | 18952776 |