EC number:1.1.1.380

Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.380
Description:L-gulonate 5-dehydrogenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.380
BRENDA Enzyme Link: BRENDA 1.1.1.380
KEGG Enzyme Link: KEGG1.1.1.380
BioCyc Enzyme Link: BioCyc 1.1.1.380
ExPASy Enzyme Link: ExPASy1.1.1.380
EC2PDB Enzyme Link: EC2PDB 1.1.1.380
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.380
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.380
IntEnz Enzyme Link: IntEnz 1.1.1.380
MEDLINE Enzyme Link: MEDLINE 1.1.1.380

EC number:1.1.1.380

MSA:

1.1.1.380;
Phylogenetic Tree:

1.1.1.380;
Uniprot:
M-CSA:
RHEA:43496 L-gulonate + NAD(+) = H(+) + keto-D-fructuronate + NADH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
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References

TitleAuthorsDatePubMed ID
The pathway for L-gulonate catabolism in Escherichia coli K-12 and Salmonella typhimurium LT-2.Cooper RA1980 Jun 166993236
Investigating the physiological roles of low-efficiency D-mannonate and D-gluconate dehydratases in the enolase superfamily: pathways for the catabolism of L-gulonate and L-idonate.Wichelecki DJ, Vendiola JA, Jones AM, Al-Obaidi N, Almo SC, Gerlt JA2014 Sep 925145794
Prediction of enzymatic pathways by integrative pathway mapping.Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, Gerlt JA, Jacobson MP, Shoichet BK, Sali A2018 Jan 2929377793