EC number:1.1.1.39

Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.39
Description:Malate dehydrogenase (decarboxylating).
Alternative Name: Pyruvic-malic carboxylase.
NAD-malic enzyme.
Malic enzyme.
Prosite: PDOC00294;
PDB:
PDBScop
Cath: 1.20.1370.30; 3.30.2330.30; 3.40.50.720; 3.40.50.10380;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.39
BRENDA Enzyme Link: BRENDA 1.1.1.39
KEGG Enzyme Link: KEGG1.1.1.39
BioCyc Enzyme Link: BioCyc 1.1.1.39
ExPASy Enzyme Link: ExPASy1.1.1.39
EC2PDB Enzyme Link: EC2PDB 1.1.1.39
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.39
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.39
IntEnz Enzyme Link: IntEnz 1.1.1.39
MEDLINE Enzyme Link: MEDLINE 1.1.1.39

EC number:1.1.1.39

MSA:

1.1.1.39;
Phylogenetic Tree:

1.1.1.39;
Uniprot:
M-CSA:
RHEA:12653 (S)-malate + NAD(+) = CO2 + NADH + pyruvate
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[C;H0;+0:10](-[OH;+0:11])-[CH2;+0:12]-[CH;+0:13](-[*:14])-[OH;+0:15]>>[*:14]-[C;H0;+0:13](-[CH3;+0:12])=[O;H0;+0:15].[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]=[C;H0;+0:10]=[O;H0;+0:11]
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