EC number:1.1.1.57
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.57 | ||
|---|---|---|---|
| Description: | Fructuronate reductase. | ||
| Alternative Name: |
Mannonic dehydrogenase. D-mannonate oxidoreductase. D-mannonate dehydrogenase. | ||
| Prosite: | PDOC00751; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.57 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.57 |
| KEGG Enzyme Link: | KEGG1.1.1.57 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.57 |
| ExPASy Enzyme Link: | ExPASy1.1.1.57 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.57 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.57 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.57 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.57 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.57 |
| RHEA:51652 | D-mannonate + NAD(+) = H(+) + keto-D-tagaturonate + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Uronic acid metabolism in bacteria. II. Purification and properties of D-altronic acid and D-mannonic acid dehydrogenases in Escherichia coli. | HICKMAN J, ASHWELL G | 1960 Jun | 14401695 |
| RHEA:15729 | D-mannonate + NAD(+) = H(+) + keto-D-fructuronate + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Uronic acid metabolism in bacteria. II. Purification and properties of D-altronic acid and D-mannonic acid dehydrogenases in Escherichia coli. | HICKMAN J, ASHWELL G | 1960 Jun | 14401695 |
| Catabolism of galacturonic and glucuronic acids by Erwinia carotovora. | KILGORE WW, STARR MP | 1959 Sep | 14409051 |
| Prediction of enzymatic pathways by integrative pathway mapping. | Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, Gerlt JA, Jacobson MP, Shoichet BK, Sali A | 2018 Jan 29 | 29377793 |