Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.1 With NAD+ or NADP+ as acceptor
ID:1.1.1.72
Description:Glycerol dehydrogenase (NADP(+)).
Prosite: PDOC00061;
PDB:
PDBScop

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.1.72
BRENDA Enzyme Link: BRENDA 1.1.1.72
KEGG Enzyme Link: KEGG1.1.1.72
BioCyc Enzyme Link: BioCyc 1.1.1.72
ExPASy Enzyme Link: ExPASy1.1.1.72
EC2PDB Enzyme Link: EC2PDB 1.1.1.72
ExplorEnz Enzyme Link: ExplorEnz 1.1.1.72
PRIAM enzyme-specific profiles Link: PRIAM 1.1.1.72
IntEnz Enzyme Link: IntEnz 1.1.1.72
MEDLINE Enzyme Link: MEDLINE 1.1.1.72
MSA:

1.1.1.72;

Phylogenetic Tree:

1.1.1.72;

Uniprot:
M-CSA:
RHEA:23592 glycerol + NADP(+) = D-glyceraldehyde + H(+) + NADPH
RULE(radius=1) [*:1]-[CH2;+0:2]-[OH;+0:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina.Liepins J, Kuorelahti S, Penttilä M, Richard P2006 Sep16930134
In vivo role of aldehyde reductase.Takahashi M, Miyata S, Fujii J, Inai Y, Ueyama S, Araki M, Soga T, Fujinawa R, Nishitani C, Ariki S, Shimizu T, Abe T, Ihara Y, Nishikimi M, Kozutsumi Y, Taniguchi N, Kuroki Y2012 Nov22820017
Characterisation of a recombinant NADP-dependent glycerol dehydrogenase from Gluconobacter oxydans and its application in the production of L-glyceraldehyde.Richter N, Neumann M, Liese A, Wohlgemuth R, Eggert T, Hummel W2009 Jul 2019579248
Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism.Crosas B, Hyndman DJ, Gallego O, Martras S, Parés X, Flynn TG, Farrés J2003 Aug 112732097