EC number:1.1.1.77
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.1.1.77 | ||
|---|---|---|---|
| Description: | Lactaldehyde reductase. | ||
| Alternative Name: |
Propanediol oxidoreductase. | ||
| Prosite: | PDOC00059; | ||
| PDB: |
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| Cath: | 1.20.1090.10; 3.40.50.1970; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.1.77 |
| BRENDA Enzyme Link: | BRENDA 1.1.1.77 |
| KEGG Enzyme Link: | KEGG1.1.1.77 |
| BioCyc Enzyme Link: | BioCyc 1.1.1.77 |
| ExPASy Enzyme Link: | ExPASy1.1.1.77 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.1.77 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.1.77 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.1.77 |
| IntEnz Enzyme Link: | IntEnz 1.1.1.77 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.1.77 |
| RHEA:23872 | (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[OH;+0:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| THE METABOLISM OF LACTALDEHYDE. VI. THE REDUCTION OF D- AND L-LACTALDEHYDE IN RAT LIVER. | TING SM, SELLINGER OZ, MILLER ON | 1964 Aug 26 | 14203169 |
| RHEA:15933 | (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[OH;+0:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of an iron-dependent group III dehydrogenase that interconverts L-lactaldehyde and L-1,2-propanediol in Escherichia coli. | Montella C, Bellsolell L, Pérez-Luque R, Badía J, Baldoma L, Coll M, Aguilar J | 2005 Jul | 15995211 |
| THE METABOLISM OF LACTALDEHYDE. VI. THE REDUCTION OF D- AND L-LACTALDEHYDE IN RAT LIVER. | TING SM, SELLINGER OZ, MILLER ON | 1964 Aug 26 | 14203169 |