EC number:1.1.2.3

Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.2 With a cytochrome as acceptor
ID:1.1.2.3
Description:L-lactate dehydrogenase (cytochrome).
Alternative Name: Lactic acid dehydrogenase.
L-lactate ferricytochrome c oxidoreductase.
Cytochrome b2.
Prosite: PDOC00482; PDOC00170;
PDB:
PDBScop
1GYL 8058077; 8058078; 8058077; 8058078;
1GOX 8058077; 8058078;
1AL8 8058077; 8058078;
1AL7 8058077; 8058078;
2A85 8058077; 8058073; 8058074; 8058078;
 » show all
Cath: 3.20.20.70; 3.10.120.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.2.3
BRENDA Enzyme Link: BRENDA 1.1.2.3
KEGG Enzyme Link: KEGG1.1.2.3
BioCyc Enzyme Link: BioCyc 1.1.2.3
ExPASy Enzyme Link: ExPASy1.1.2.3
EC2PDB Enzyme Link: EC2PDB 1.1.2.3
ExplorEnz Enzyme Link: ExplorEnz 1.1.2.3
PRIAM enzyme-specific profiles Link: PRIAM 1.1.2.3
IntEnz Enzyme Link: IntEnz 1.1.2.3
MEDLINE Enzyme Link: MEDLINE 1.1.2.3

EC number:1.1.2.3

MSA:

1.1.2.3;
Phylogenetic Tree:

1.1.2.3;
Uniprot:
M-CSA:
RHEA:19909 (S)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H(+) + pyruvate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[Fe+3;H0:5].[Fe+3;H0:6]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[Fe+2;H0:5].[Fe+2;H0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Yeast lactic dehydrogenase and cytochrome b(2).Bach SJ, Dixon M, Zerfas LG194616747991
Lactic dehydrogenase and cytochrome b2 of baker's yeast. Enzymic and chemical properties of the crystalline enzyme.APPLEBY CA, MORTON RK1959 Nov13793977
Lactic dehydrogenase and cytochrome b2 of baker's yeast; purification and crystallization.APPLEBY CA, MORTON RK1959 Mar13638255