EC number:1.1.3.23
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.3 With oxygen as acceptor |
| ID: | 1.1.3.23 |
|---|---|
| Description: | Thiamine oxidase. |
| Alternative Name: |
Thiamine dehydrogenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.3.23 |
| BRENDA Enzyme Link: | BRENDA 1.1.3.23 |
| KEGG Enzyme Link: | KEGG1.1.3.23 |
| BioCyc Enzyme Link: | BioCyc 1.1.3.23 |
| ExPASy Enzyme Link: | ExPASy1.1.3.23 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.3.23 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.3.23 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.3.23 |
| IntEnz Enzyme Link: | IntEnz 1.1.3.23 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.3.23 |
| RHEA:21280 | H2O + 2 O2 + thiamine = H(+) + 2 H2O2 + thiamine acetate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[OH;+0:3].[O;H0;+0:4]=[O;H0;+0:5].[O;H0;+0:6]=[O;H0;+0:7].[OH2;+0:8]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:3])-[OH;+0:8].[OH;+0:4]-[OH;+0:5].[OH;+0:6]-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Bacterial metabolism of thiamine. 3. Metabolism of thiamine to 3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methyl-thiazole-5-acetic acid (thiamine acetic acid) by a flavoprotein isolated from a soil microorganism. | Neal RA | 1970 May 25 | 4987737 |
| Evidence for an aldehyde intermediate in the catalytic mechanism of thiamine oxidase. | Gomez-Moreno C, Edmondson DE | 1985 May 15 | 2988447 |
| Structural elucidation and properties of 8alpha-(N1-histidyl)riboflavin: the flavin component of thiamine dehydrogenase and beta-cyclopiazonate oxidocyclase. | Edmondson DE, Kenney WC, Singer TP | 1976 Jul 13 | 8076 |