Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.3 With oxygen as acceptor
ID:1.1.3.41
Description:Alditol oxidase.
Alternative Name: Xylitol oxidase.
Prosite: PDOC00674;
PDB:
PDBScop
Cath: 1.10.45.10; 3.30.43.10; 3.30.465.10; 3.30.70.2520; 3.30.70.2530;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.3.41
BRENDA Enzyme Link: BRENDA 1.1.3.41
KEGG Enzyme Link: KEGG1.1.3.41
BioCyc Enzyme Link: BioCyc 1.1.3.41
ExPASy Enzyme Link: ExPASy1.1.3.41
EC2PDB Enzyme Link: EC2PDB 1.1.3.41
ExplorEnz Enzyme Link: ExplorEnz 1.1.3.41
PRIAM enzyme-specific profiles Link: PRIAM 1.1.3.41
IntEnz Enzyme Link: IntEnz 1.1.3.41
MEDLINE Enzyme Link: MEDLINE 1.1.3.41
MSA:

1.1.3.41;

Phylogenetic Tree:

1.1.3.41;

Uniprot:
M-CSA:
RHEA:25908 an alditol + O2 = an aldose + H2O2
RULE(radius=1) [*:1]-[CH2;+0:2]-[OH;+0:3].[O;H0;+0:4]=[O;H0;+0:5]>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[OH;+0:4]-[OH;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Structural analysis of the catalytic mechanism and stereoselectivity in Streptomyces coelicolor alditol oxidase.Forneris F, Heuts DP, Delvecchio M, Rovida S, Fraaije MW, Mattevi A2008 Jan 2218154360
Discovery, characterization, and kinetic analysis of an alditol oxidase from Streptomyces coelicolor.Heuts DP, van Hellemond EW, Janssen DB, Fraaije MW2007 Jul 1317517896
Isolation, characterization, and molecular cloning of a thermostable xylitol oxidase from Streptomyces sp. IKD472.Yamashita M, Omura H, Okamoto E, Furuya Y, Yabuuchi M, Fukahi K, Murooka Y200016232758

RHEA:22308 O2 + xylitol = D-xylose + H2O2
RULE(radius=1) ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[OH;+0:5]).[O;H0;+0:6]=[O;H0;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:5]-[*:4].[OH;+0:6]-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Structural analysis of the catalytic mechanism and stereoselectivity in Streptomyces coelicolor alditol oxidase.Forneris F, Heuts DP, Delvecchio M, Rovida S, Fraaije MW, Mattevi A2008 Jan 2218154360
Discovery, characterization, and kinetic analysis of an alditol oxidase from Streptomyces coelicolor.Heuts DP, van Hellemond EW, Janssen DB, Fraaije MW2007 Jul 1317517896
Isolation, characterization, and molecular cloning of a thermostable xylitol oxidase from Streptomyces sp. IKD472.Yamashita M, Omura H, Okamoto E, Furuya Y, Yabuuchi M, Fukahi K, Murooka Y200016232758