EC Tree |
1. Oxidoreductases |
1.1 Acting on the CH-OH group of donors |
1.1.3 With oxygen as acceptor |
ID: | 1.1.3.44 |
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Description: | 6'''-hydroxyneomycin C oxidase. |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.1.3.44 |
BRENDA Enzyme Link: | BRENDA 1.1.3.44 |
KEGG Enzyme Link: | KEGG1.1.3.44 |
BioCyc Enzyme Link: | BioCyc 1.1.3.44 |
ExPASy Enzyme Link: | ExPASy1.1.3.44 |
EC2PDB Enzyme Link: | EC2PDB 1.1.3.44 |
ExplorEnz Enzyme Link: | ExplorEnz 1.1.3.44 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.1.3.44 |
IntEnz Enzyme Link: | IntEnz 1.1.3.44 |
MEDLINE Enzyme Link: | MEDLINE 1.1.3.44 |
RHEA:34047 | 6'''-deamino-6'''-hydroxyneomycin C + O2 = 6'''-deamino-6'''-oxoneomycin C + H2O2 |
RULE(radius=1) | [*:1]-[CH2;+0:2]-[OH;+0:3].[O;H0;+0:4]=[O;H0;+0:5]>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[OH;+0:4]-[OH;+0:5] |
Reaction | ![]() |
Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
Title | Authors | Date | PubMed ID |
---|---|---|---|
The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin. | Clausnitzer D, Piepersberg W, Wehmeier UF | 2011 Sep | 21689223 |
Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin. | Huang F, Spiteller D, Koorbanally NA, Li Y, Llewellyn NM, Spencer JB | 2007 Feb 12 | 17206729 |