EC number:1.1.3.45

Enzyme

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     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.3 With oxygen as acceptor
ID:1.1.3.45
Description:Aclacinomycin-N oxidase.
Alternative Name: AknOx.
Aclacinomycin oxidoreductase.
Cath: 3.30.465.40; 3.40.462.20;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.3.45
BRENDA Enzyme Link: BRENDA 1.1.3.45
KEGG Enzyme Link: KEGG1.1.3.45
BioCyc Enzyme Link: BioCyc 1.1.3.45
ExPASy Enzyme Link: ExPASy1.1.3.45
EC2PDB Enzyme Link: EC2PDB 1.1.3.45
ExplorEnz Enzyme Link: ExplorEnz 1.1.3.45
PRIAM enzyme-specific profiles Link: PRIAM 1.1.3.45
IntEnz Enzyme Link: IntEnz 1.1.3.45
MEDLINE Enzyme Link: MEDLINE 1.1.3.45

EC number:1.1.3.45

MSA:

1.1.3.45;
Phylogenetic Tree:

1.1.3.45;
Uniprot:
M-CSA:
RHEA:37423 aclacinomycin N + O2 = aclacinomycin A + H2O2
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[O;H0;+0:5]=[O;H0;+0:6]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[OH;+0:5]-[OH;+0:6]
Reaction
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References

TitleAuthorsDatePubMed ID
Aclacinomycin oxidoreductase (AknOx) from the biosynthetic pathway of the antibiotic aclacinomycin is an unusual flavoenzyme with a dual active site.Alexeev I, Sultana A, Mäntsälä P, Niemi J, Schneider G2007 Apr 1017395717
Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning.Sultana A, Alexeev I, Kursula I, Mäntsälä P, Niemi J, Schneider G2007 Feb17242508