EC number:1.1.3.9
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.3 With oxygen as acceptor |
| ID: | 1.1.3.9 |
|---|---|
| Description: | Galactose oxidase. |
| Alternative Name: |
Beta-galactose oxidase. |
| Cath: | 2.130.10.80; 2.60.120.260; 2.60.40.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.3.9 |
| BRENDA Enzyme Link: | BRENDA 1.1.3.9 |
| KEGG Enzyme Link: | KEGG1.1.3.9 |
| BioCyc Enzyme Link: | BioCyc 1.1.3.9 |
| ExPASy Enzyme Link: | ExPASy1.1.3.9 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.3.9 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.3.9 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.3.9 |
| IntEnz Enzyme Link: | IntEnz 1.1.3.9 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.3.9 |
| RHEA:24160 | D-galactose + O2 = D-galacto-hexodialdose + H2O2 |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[OH;+0:3])-[O;H0;+0:4]-[*:5]-[CH2;+0:6]-[OH;+0:7].[O;H0;+0:8]=[O;H0;+0:9]>>([*:1]-[CH;+0:2]=[O;H0;+0:3].[O;H0;+0:7]=[CH;+0:6]-[*:5]-[OH;+0:4]).[OH;+0:8]-[OH;+0:9] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structure and mechanism of galactose oxidase. The free radical site. | Baron AJ, Stevens C, Wilmot C, Seneviratne KD, Blakeley V, Dooley DM, Phillips SE, Knowles PF, McPherson MJ | 1994 Oct 7 | 7929198 |
| The stacking tryptophan of galactose oxidase: a second-coordination sphere residue that has profound effects on tyrosyl radical behavior and enzyme catalysis. | Rogers MS, Tyler EM, Akyumani N, Kurtis CR, Spooner RK, Deacon SE, Tamber S, Firbank SJ, Mahmoud K, Knowles PF, Phillips SE, McPherson MJ, Dooley DM | 2007 Apr 17 | 17385891 |
| Enhanced fructose oxidase activity in a galactose oxidase variant. | Deacon SE, Mahmoud K, Spooner RK, Firbank SJ, Knowles PF, Phillips SE, McPherson MJ | 2004 Jul 5 | 15239055 |
| Structural and kinetic studies of a series of mutants of galactose oxidase identified by directed evolution. | Wilkinson D, Akumanyi N, Hurtado-Guerrero R, Dawkes H, Knowles PF, Phillips SE, McPherson MJ | 2004 Feb | 15047910 |
| The D-galactose oxidase of Polyporus circinatus. | AVIGAD G, AMARAL D, ASENSIO C, HORECKER BL | 1962 Sep | 13863403 |