Enzyme

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EC Tree
     1. Oxidoreductases
        1.1 Acting on the CH-OH group of donors
            1.1.9 With a copper protein as acceptor
ID:1.1.9.1
Description:Alcohol dehydrogenase (azurin).
Alternative Name: QHEDH.
Cath: 1.10.760.10; 2.140.10.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.1.9.1
BRENDA Enzyme Link: BRENDA 1.1.9.1
KEGG Enzyme Link: KEGG1.1.9.1
BioCyc Enzyme Link: BioCyc 1.1.9.1
ExPASy Enzyme Link: ExPASy1.1.9.1
EC2PDB Enzyme Link: EC2PDB 1.1.9.1
ExplorEnz Enzyme Link: ExplorEnz 1.1.9.1
PRIAM enzyme-specific profiles Link: PRIAM 1.1.9.1
IntEnz Enzyme Link: IntEnz 1.1.9.1
MEDLINE Enzyme Link: MEDLINE 1.1.9.1
MSA:

1.1.9.1;

Phylogenetic Tree:

1.1.9.1;

Uniprot:
M-CSA:
RHEA:51148 a primary alcohol + 2 oxidized [azurin] = an aldehyde + 2 H(+) + 2 reduced [azurin]
RULE(radius=1) [*:1]-[CH2;+0:2]-[OH;+0:3].[Cu+2;H0:4].[Cu+2;H0:5]>>[*:1]-[CH;+0:2]=[O;H0;+0:3].[Cu+;H0:4].[Cu+;H0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Three distinct quinoprotein alcohol dehydrogenases are expressed when Pseudomonas putida is grown on different alcohols.Toyama H, Fujii A, Matsushita K, Shinagawa E, Ameyama M, Adachi O1995 May7730276
Characterization of the interaction between PQQ and heme c in the quinohemoprotein ethanol dehydrogenase from Comamonas testosteroni.de Jong GA, Caldeira J, Sun J, Jongejan JA, de Vries S, Loehr TM, Moura I, Moura JJ, Duine JA1995 Jul 257626615
Quinohaemoprotein alcohol dehydrogenase apoenzyme from Pseudomonas testosteroni.Groen BW, van Kleef MA, Duine JA1986 Mar 153521592
Structure at 1.9 A resolution of a quinohemoprotein alcohol dehydrogenase from Pseudomonas putida HK5.Chen ZW, Matsushita K, Yamashita T, Fujii TA, Toyama H, Adachi O, Bellamy HD, Mathews FS2002 Jun12057198
Crystal structure of quinohemoprotein alcohol dehydrogenase from Comamonas testosteroni: structural basis for substrate oxidation and electron transfer.Oubrie A, Rozeboom HJ, Kalk KH, Huizinga EG, Dijkstra BW2002 Feb 111714714
Electron transfer from quinohemoprotein alcohol dehydrogenase to blue copper protein azurin in the alcohol oxidase respiratory chain of Pseudomonas putida HK5.Matsushita K, Yamashita T, Aoki N, Toyama H, Adachi O1999 May 1110320337