EC number:1.1.98.6
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.98 With other, known, physiological acceptors |
| ID: | 1.1.98.6 |
|---|---|
| Description: | Ribonucleoside-triphosphate reductase (formate). |
| Alternative Name: |
Anaerobic ribonucleoside-triphosphate reductase. |
| Cath: | 1.10.1650.20; 1.10.620.20; 3.20.70.20; 3.30.160.90; 3.30.1620.10; 3.90.1390.10; 2.170.16.10; 3.10.28.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.98.6 |
| BRENDA Enzyme Link: | BRENDA 1.1.98.6 |
| KEGG Enzyme Link: | KEGG1.1.98.6 |
| BioCyc Enzyme Link: | BioCyc 1.1.98.6 |
| ExPASy Enzyme Link: | ExPASy1.1.98.6 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.98.6 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.98.6 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.98.6 |
| IntEnz Enzyme Link: | IntEnz 1.1.98.6 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.98.6 |
| RHEA:51476 | a ribonucleoside 5'-triphosphate + formate + H(+) = a 2'-deoxyribonucleoside 5'-triphosphate + CO2 + H2O |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]=[CH;+0:6]-[OH;+0:7].[H+;H0:8]>>[*:1]-[CH2;+0:2]-[*:3].[*:5]=[C;H0;+0:6]=[O;H0;+0:7].[OH2;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Activation of the anaerobic ribonucleotide reductase from Escherichia coli. The essential role of the iron-sulfur center for S-adenosylmethionine reduction. | Ollagnier S, Mulliez E, Schmidt PP, Eliasson R, Gaillard J, Deronzier C, Bergman T, Gräslund A, Reichard P, Fontecave M | 1997 Sep 26 | 9305874 |
| An iron-sulfur center and a free radical in the active anaerobic ribonucleotide reductase of Escherichia coli. | Mulliez E, Fontecave M, Gaillard J, Reichard P | 1993 Feb 5 | 8381402 |
| Formate is the hydrogen donor for the anaerobic ribonucleotide reductase from Escherichia coli. | Mulliez E, Ollagnier S, Fontecave M, Eliasson R, Reichard P | 1995 Sep 12 | 7568012 |
| A chemically competent thiosulfuranyl radical on the Escherichia coli class III ribonucleotide reductase. | Wei Y, Mathies G, Yokoyama K, Chen J, Griffin RG, Stubbe J | 2014 Jun 25 | 24827372 |
| Characterization of components of the anaerobic ribonucleotide reductase system from Escherichia coli. | Eliasson R, Pontis E, Fontecave M, Gerez C, Harder J, Jörnvall H, Krook M, Reichard P | 1992 Dec 15 | 1460049 |