EC number:1.1.99.31
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.1 Acting on the CH-OH group of donors |
| 1.1.99 With unknown physiological acceptors |
| ID: | 1.1.99.31 | ||
|---|---|---|---|
| Description: | (S)-mandelate dehydrogenase. | ||
| Alternative Name: |
MDH. L(+)-mandelate dehydrogenase. | ||
| Prosite: | PDOC00482; | ||
| PDB: |
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| Cath: | 3.20.20.70; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.1.99.31 |
| BRENDA Enzyme Link: | BRENDA 1.1.99.31 |
| KEGG Enzyme Link: | KEGG1.1.99.31 |
| BioCyc Enzyme Link: | BioCyc 1.1.99.31 |
| ExPASy Enzyme Link: | ExPASy1.1.99.31 |
| EC2PDB Enzyme Link: | EC2PDB 1.1.99.31 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.1.99.31 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.1.99.31 |
| IntEnz Enzyme Link: | IntEnz 1.1.99.31 |
| MEDLINE Enzyme Link: | MEDLINE 1.1.99.31 |
EC number:1.1.99.31
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:15749 | (S)-mandelate + A = AH2 + phenylglyoxylate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| L-Mandelate dehydrogenase from Rhodotorula graminis: cloning, sequencing and kinetic characterization of the recombinant enzyme and its independently expressed flavin domain. | Illias RM, Sinclair R, Robertson D, Neu A, Chapman SK, Reid GA | 1998 Jul 1 | 9639569 |
| Role of glycine 81 in (S)-mandelate dehydrogenase from Pseudomonas putida in substrate specificity and oxidase activity. | Dewanti AR, Xu Y, Mitra B | 2004 Aug 24 | 15311930 |
| Esters of mandelic acid as substrates for (S)-mandelate dehydrogenase from Pseudomonas putida: implications for the reaction mechanism. | Dewanti AR, Xu Y, Mitra B | 2004 Feb 24 | 14967029 |
| High resolution structures of an oxidized and reduced flavoprotein. The water switch in a soluble form of (S)-mandelate dehydrogenase. | Sukumar N, Dewanti AR, Mitra B, Mathews FS | 2004 Jan 30 | 14604988 |
| Structure of an active soluble mutant of the membrane-associated (S)-mandelate dehydrogenase. | Sukumar N, Xu Y, Gatti DL, Mitra B, Mathews FS | 2001 Aug 21 | 11502180 |
| (S)-Mandelate dehydrogenase from Pseudomonas putida: mechanistic studies with alternate substrates and pH and kinetic isotope effects. | Lehoux IE, Mitra B | 1999 May 4 | 10231535 |