EC number:1.10.3.1

Enzyme

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EC Tree
     1. Oxidoreductases
        1.10 Acting on diphenols and related substances as donors
            1.10.3 With oxygen as acceptor
ID:1.10.3.1
Description:Catechol oxidase.
Alternative Name: Tyrosinase.
Polyphenol oxidase.
Phenolase.
o-diphenolase.
Diphenol oxidase.
Prosite: PDOC00398;
PDB:
PDBScop
1BUG 8025691; 8038070; 8025691; 8038070;
1BT2 8025691; 8038070; 8025691; 8038070;
1BT1 8025691; 8038070; 8025691; 8038070;
1BT3 8025691; 8038070;
1HCY 8025687; 8025690; 8038066; 8038069; 8054964; 8054965; 8025687; 8025690; 8038066; 8038069; 8054964; 8054965; 8025687; 8025690; 8038066; 8038069; 8054964; 8054965; 8025687; 8025690; 8038066; 8038069; 8054964; 8054965; 8025687; 8025690; 8038066; 8038069; 8054964; 8054965; 8025687; 8025690; 8038066; 8038069; 8054964; 8054965;
 » show all
Cath: 1.10.1280.10; 1.20.1370.10; 2.60.40.1520;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.10.3.1
BRENDA Enzyme Link: BRENDA 1.10.3.1
KEGG Enzyme Link: KEGG1.10.3.1
BioCyc Enzyme Link: BioCyc 1.10.3.1
ExPASy Enzyme Link: ExPASy1.10.3.1
EC2PDB Enzyme Link: EC2PDB 1.10.3.1
ExplorEnz Enzyme Link: ExplorEnz 1.10.3.1
PRIAM enzyme-specific profiles Link: PRIAM 1.10.3.1
IntEnz Enzyme Link: IntEnz 1.10.3.1
MEDLINE Enzyme Link: MEDLINE 1.10.3.1

EC number:1.10.3.1

MSA:

1.10.3.1;
Phylogenetic Tree:

1.10.3.1;
Uniprot:
M-CSA:
RHEA:21632 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O
RULE(radius=1) [O;H0;+0:1]=[O;H0;+0:2].[OH;+0:3]-[c;H0;+0:4]1:[cH;+0:5]:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9]:1-[OH;+0:10].[OH;+0:11]-[c;H0;+0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[cH;+0:16]:[c;H0;+0:17]:1-[OH;+0:18]>>[O;H0;+0:3]=[C;H0;+0:4]1-[CH;+0:5]=[CH;+0:6]-[CH;+0:7]=[CH;+0:8]-[C;H0;+0:9]-1=[O;H0;+0:10].[O;H0;+0:11]=[C;H0;+0:12]1-[CH;+0:13]=[CH;+0:14]-[CH;+0:15]=[CH;+0:16]-[C;H0;+0:17]-1=[O;H0;+0:18].[OH2;+0:1].[OH2;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Cloning, sequencing, purification, and crystal structure of Grenache (Vitis vinifera) polyphenol oxidase.Virador VM, Reyes Grajeda JP, Blanco-Labra A, Mendiola-Olaya E, Smith GM, Moreno A, Whitaker JR2010 Jan 2720039636
The crystal structure of catechol oxidase: new insight into the function of type-3 copper proteins.Gerdemann C, Eicken C, Krebs B2002 Mar11900522