EC number:1.11.1.16
| ID: | 1.11.1.16 | ||
|---|---|---|---|
| Description: | Versatile peroxidase. | ||
| Alternative Name: |
VP. Polyvalent peroxidase. Hybrid peroxidase. | ||
| Prosite: | PDOC00394; | ||
| PDB: |
|
||
| Cath: | 1.10.420.10; 1.10.520.10; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.11.1.16 |
| BRENDA Enzyme Link: | BRENDA 1.11.1.16 |
| KEGG Enzyme Link: | KEGG1.11.1.16 |
| BioCyc Enzyme Link: | BioCyc 1.11.1.16 |
| ExPASy Enzyme Link: | ExPASy1.11.1.16 |
| EC2PDB Enzyme Link: | EC2PDB 1.11.1.16 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.11.1.16 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.11.1.16 |
| IntEnz Enzyme Link: | IntEnz 1.11.1.16 |
| MEDLINE Enzyme Link: | MEDLINE 1.11.1.16 |
EC number:1.11.1.16
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:22776 | 2 H(+) + H2O2 + 2 Mn(2+) = 2 H2O + 2 Mn(3+) |
| RULE(radius=1) | [H+;H0:1].[H+;H0:2].[Mn+2;H0:3].[Mn+2;H0:4].[OH;+0:5]-[OH;+0:6]>>[Mn+3;H0:3].[Mn+3;H0:4].[OH2;+0:5].[OH2;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Comparison of ligninase-I and peroxidase-M2 from the white-rot fungus Phanerochaete chrysosporium. | Paszczyński A, Huynh VB, Crawford R | 1986 Feb 1 | 3080953 |
| Manganese peroxidase from the lignin-degrading basidiomycete Phanerochaete chrysosporium. Transient state kinetics and reaction mechanism. | Wariishi H, Dunford HB, MacDonald ID, Gold MH | 1989 Feb 25 | 2914954 |
| Characterization of reactions catalyzed by manganese peroxidase from Phanerochaete chrysosporium. | Aitken MD, Irvine RL | 1990 Feb 1 | 2306104 |
| Identification and characterization of a multifunctional dye peroxidase from a lignin-reactive bacterium. | Brown ME, Barros T, Chang MC | 2012 Dec 21 | 23054399 |
| Stability testing of ligninase and Mn-peroxidase from Phanerochaete chrysosporium. | Aitken MD, Irvine RL | 1989 Dec 5 | 18588065 |
| The catalytic site of manganese peroxidase. Regiospecific addition of sodium azide and alkylhydrazines to the heme group. | Harris RZ, Wariishi H, Gold MH, Ortiz de Montellano PR | 1991 May 15 | 1851156 |
| Manganese(II) oxidation by manganese peroxidase from the basidiomycete Phanerochaete chrysosporium. Kinetic mechanism and role of chelators. | Wariishi H, Valli K, Gold MH | 1992 Nov 25 | 1429709 |
| RHEA:22396 | 1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + H2O2 = 4-hydroxy-3-methoxybenzaldehyde + glycolaldehyde + guaiacol + H2O |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[CH2;+0:4]-[OH;+0:5])-[CH;+0:6](-[*:7])-[OH;+0:8].[OH;+0:9]-[OH;+0:10]>>[*:7]-[CH;+0:6]=[O;H0;+0:8].[*:1]-[OH;+0:2].[O;H0;+0:5]=[CH;+0:4]-[CH2;+0:3]-[OH;+0:10].[OH2;+0:9] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Molecular characterization of a novel peroxidase isolated from the ligninolytic fungus Pleurotus eryngii. | Ruiz-Dueñas FJ, Martínez MJ, Martínez AT | 1999 Jan | 9987124 |
| A study on reducing substrates of manganese-oxidizing peroxidases from Pleurotus eryngii and Bjerkandera adusta. | Heinfling A, Ruiz-Dueñas FJ, Martínez MJ, Bergbauer M, Szewzyk U, Martínez AT | 1998 May 29 | 9654123 |
| Purification and catalytic properties of two manganese peroxidase isoenzymes from Pleurotus eryngii. | Martínez MJ, Ruiz-Dueñas FJ, Guillén F, Martínez AT | 1996 Apr 15 | 8647081 |
| Versatile peroxidase oxidation of high redox potential aromatic compounds: site-directed mutagenesis, spectroscopic and crystallographic investigation of three long-range electron transfer pathways. | Pérez-Boada M, Ruiz-Dueñas FJ, Pogni R, Basosi R, Choinowski T, Martínez MJ, Piontek K, Martínez AT | 2005 Nov 25 | 16246366 |
| NMR study of manganese(II) binding by a new versatile peroxidase from the white-rot fungus Pleurotus eryngii. | Banci L, Camarero S, Martínez AT, Martínez MJ, Pérez-Boada M, Pierattelli R, Ruiz-Dueñas FJ | 2003 Sep | 12884090 |
| A new versatile peroxidase from Pleurotus. | Ruiz-Dueñas FJ, Camarero S, Pérez-Boada M, Martínez MJ, Martínez AT | 2001 May | 11356138 |
| The cloning of a new peroxidase found in lignocellulose cultures of Pleurotus eryngii and sequence comparison with other fungal peroxidases. | Camarero S, Ruiz-Dueñas FJ, Sarkar S, Martínez MJ, Martínez AT | 2000 Oct 1 | 11004397 |
| Heterologous expression of Pleurotus eryngii peroxidase confirms its ability to oxidize Mn(2+) and different aromatic substrates. | Ruiz-Dueñas FJ, Martínez MJ, Martínez AT | 1999 Oct | 10508113 |
| Description of a versatile peroxidase involved in the natural degradation of lignin that has both manganese peroxidase and lignin peroxidase substrate interaction sites. | Camarero S, Sarkar S, Ruiz-Dueñas FJ, Martínez MJ, Martínez AT | 1999 Apr 9 | 10187820 |
| A search for ligninolytic peroxidases in the fungus pleurotus eryngii involving alpha-keto-gamma-thiomethylbutyric acid and lignin model dimers | Caramelo L, Martinez MJ, Martinez AT | 1999 Mar | 10049842 |