EC number:1.11.1.23

Enzyme

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     1. Oxidoreductases
        1.11 Acting on a peroxide as acceptor
            1.11.1 Peroxidases
ID:1.11.1.23
Description:(S)-2-hydroxypropylphosphonic acid epoxidase.
Alternative Name: HPP epoxidase.
2-hydroxypropylphosphonic acid epoxidase.
(S)-2-hydroxypropylphosphonate epoxidase.
Cath: 1.10.260.40; 2.60.120.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.11.1.23
BRENDA Enzyme Link: BRENDA 1.11.1.23
KEGG Enzyme Link: KEGG1.11.1.23
BioCyc Enzyme Link: BioCyc 1.11.1.23
ExPASy Enzyme Link: ExPASy1.11.1.23
EC2PDB Enzyme Link: EC2PDB 1.11.1.23
ExplorEnz Enzyme Link: ExplorEnz 1.11.1.23
PRIAM enzyme-specific profiles Link: PRIAM 1.11.1.23
IntEnz Enzyme Link: IntEnz 1.11.1.23
MEDLINE Enzyme Link: MEDLINE 1.11.1.23

EC number:1.11.1.23

MSA:

1.11.1.23;
Phylogenetic Tree:

1.11.1.23;
Uniprot:
M-CSA:
RHEA:10808 (S)-2-hydroxypropylphosphonate + H2O2 = (1R,2S)-epoxypropylphosphonate + 2 H2O
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3]-[OH;+0:4].[OH;+0:5]-[OH;+0:6]>>[*:1]-[CH;+0:2]1-[*:3]-[O;H0;+0:4]-1.[OH2;+0:6].[OH2;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterization of the epoxidase catalyzing the formation of fosfomycin from Pseudomonas syringae.Munos JW, Moon SJ, Mansoorabadi SO, Chang W, Hong L, Yan F, Liu A, Liu HW2008 Aug 1918656958
Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.Higgins LJ, Yan F, Liu P, Liu HW, Drennan CL2005 Oct 616015285