Enzyme

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EC Tree
     1. Oxidoreductases
        1.12 Acting on hydrogen as donor
            1.12.2 With a cytochrome as acceptor
ID:1.12.2.1
Description:Cytochrome-c3 hydrogenase.
Alternative Name: H(2):ferricytochrome c3 oxidoreductase.
Cytochrome hydrogenase.
Cytochrome c3 reductase.
Cath: 1.10.645.10; 4.10.480.10; 3.40.50.700;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.12.2.1
BRENDA Enzyme Link: BRENDA 1.12.2.1
KEGG Enzyme Link: KEGG1.12.2.1
BioCyc Enzyme Link: BioCyc 1.12.2.1
ExPASy Enzyme Link: ExPASy1.12.2.1
EC2PDB Enzyme Link: EC2PDB 1.12.2.1
ExplorEnz Enzyme Link: ExplorEnz 1.12.2.1
PRIAM enzyme-specific profiles Link: PRIAM 1.12.2.1
IntEnz Enzyme Link: IntEnz 1.12.2.1
MEDLINE Enzyme Link: MEDLINE 1.12.2.1
MSA:

1.12.2.1;

Phylogenetic Tree:

1.12.2.1;

Uniprot:
M-CSA:
RHEA:20625 2 [Fe(III)cytochrome c3] + H2 = 2 [Fe(II)cytochrome c3] + 2 H(+)
RULE(radius=1) [Fe+3;H0:1].[Fe+3;H0:2].[H;H0;+0:3]-[H;H0;+0:4]>>[Fe+2;H0:1].[Fe+2;H0:2].[H+;H0:3].[H+;H0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Crystal structure of the nickel-iron hydrogenase from Desulfovibrio gigas.Volbeda A, Charon MH, Piras C, Hatchikian EC, Frey M, Fontecilla-Camps JC1995 Feb 167854413
A monomolecular electron transfer chain: structure and function of cytochrome C3.Der Vartanian DV, LeGall J1974 Apr 304364940
Single crystals of hydrogenase from Desulfovibrio vulgaris Miyazaki F.Higuchi Y, Yasuoka N, Kakudo M, Katsube Y, Yagi T, Inokuchi H1987 Feb 253546297
Purification and properties of the hydrogenase of Desulfovibrio desulfuricans.SADANA JC, MOREY AV1961 Jun 1013745271
Some observations on the enzyme, hydrogenase.RIKLIS E, RITTENBERG D1961 Sep13741672
The crystal structure of a reduced [NiFeSe] hydrogenase provides an image of the activated catalytic center.Garcin E, Vernede X, Hatchikian EC, Volbeda A, Frey M, Fontecilla-Camps JC1999 May10378275