Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.12 Acting on hydrogen as donor
            1.12.98 With other, known, physiological acceptors
ID:1.12.98.2
Description:5,10-methenyltetrahydromethanopterin hydrogenase.
Alternative Name: Nonmetal hydrogenase.
N(5),N(10)-methenyltetrahydromethanopterin hydrogenase.
Hydrogen:N(5),N(10)-methenyltetrahydromethanopterin oxidoreductase.
H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase.
H(2)-dependent methylene-H(4)MPT dehydrogenase.
Cath: 1.20.120.1300; 3.40.50.720;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.12.98.2
BRENDA Enzyme Link: BRENDA 1.12.98.2
KEGG Enzyme Link: KEGG1.12.98.2
BioCyc Enzyme Link: BioCyc 1.12.98.2
ExPASy Enzyme Link: ExPASy1.12.98.2
EC2PDB Enzyme Link: EC2PDB 1.12.98.2
ExplorEnz Enzyme Link: ExplorEnz 1.12.98.2
PRIAM enzyme-specific profiles Link: PRIAM 1.12.98.2
IntEnz Enzyme Link: IntEnz 1.12.98.2
MEDLINE Enzyme Link: MEDLINE 1.12.98.2
MSA:

1.12.98.2;

Phylogenetic Tree:

1.12.98.2;

Uniprot:
M-CSA:
RHEA:20017 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 = 5,10-methylenetetrahydromethanopterin + H(+)
RULE(radius=1) [*:1]-[CH;+0:2]=[N+;H0:3](-[*:4])-[*:5].[H;H0;+0:6]-[H;H0;+0:7]>>[*:1]-[CH2;+0:2]-[N;H0;+0:3](-[*:4])-[*:5].[H+;H0:6]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Purification, properties and primary structure of H2-forming N5 ,N10 -methylenetetrahydromethanopterin dehydrogenase from Methanococcus thermolithotrophicus.Hartmann GC, Klein AR, Linder M, Thauer RK1996 Mar8599536
H2-forming N5, N10-methylenetetrahydromethanopterin dehydrogenase from Methanobacterium thermoautotrophicum catalyzes a stereoselective hydride transfer as determined by two-dimensional NMR spectroscopy.Schleucher J, Griesinger C, Schwörer B, Thauer RK1994 Apr 58142403
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase: mechanism of H2 formation analyzed using hydrogen isotopes.Klein AR, Fernández VM, Thauer RK1995 Jul 177628605
Participative management.Wheeler A1978 Mar 16628605