EC number:1.13.11.15

Enzyme

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     1. Oxidoreductases
        1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
            1.13.11 With incorporation of two atoms of oxygen
ID:1.13.11.15
Description:3,4-dihydroxyphenylacetate 2,3-dioxygenase.
Alternative Name: HPC dioxygenase.
Homoprotocatechuate 2,3-dioxygenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.13.11.15
BRENDA Enzyme Link: BRENDA 1.13.11.15
KEGG Enzyme Link: KEGG1.13.11.15
BioCyc Enzyme Link: BioCyc 1.13.11.15
ExPASy Enzyme Link: ExPASy1.13.11.15
EC2PDB Enzyme Link: EC2PDB 1.13.11.15
ExplorEnz Enzyme Link: ExplorEnz 1.13.11.15
PRIAM enzyme-specific profiles Link: PRIAM 1.13.11.15
IntEnz Enzyme Link: IntEnz 1.13.11.15
MEDLINE Enzyme Link: MEDLINE 1.13.11.15

EC number:1.13.11.15

MSA:

1.13.11.15;
Phylogenetic Tree:

1.13.11.15;
Uniprot:
M-CSA:
RHEA:15633 3,4-dihydroxyphenylacetate + O2 = 2-hydroxy-5-carboxymethylmuconate semialdehyde + H(+)
RULE(radius=1) [*:1]-[c;H0;+0:2]1:[cH;+0:3]:[c;H0;+0:4](-[OH;+0:5]):[c;H0;+0:6](-[*:7]):[cH;+0:8]:[cH;+0:9]:1.[O;H0;+0:10]=[O;H0;+0:11]>>[*:1]-[C;H0;+0:2](-[CH;+0:3]=[O;H0;+0:10])=[CH;+0:9]-[CH;+0:8]=[C;H0;+0:6](-[*:7])-[C;H0;+0:4](=[O;H0;+0:5])-[OH;+0:11]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Control of meta-cleavage degradation of 4-hydroxyphenylacetate in Pseudomonas putida.Barbour MG, Bayly RC1981 Sep6895079
Degradation of (+/-)-synephrine by Arthrobacter synephrinum. Oxidation of 3,4-dihydroxyphenylacetate to 2-hydroxy-5-carboxymethyl-muconate semialdehyde.Kutty RK, Devi NA, Veeraswamy M, Ramesh S, Rao PV1977 Oct 1588248
METABOLISM OF P-HYDROXYPHENYLACETIC ACID IN PSEUDOMONAS OVALIS.ADACHI K, TAKEDA Y, SENOH S, KITA H1964 Dec 914263147