EC Tree |
1. Oxidoreductases |
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
1.13.11 With incorporation of two atoms of oxygen |
ID: | 1.13.11.45 |
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Description: | Linoleate 11-lipoxygenase. |
Alternative Name: |
Manganese lipoxygenase. Linoleate dioxygenase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.13.11.45 |
BRENDA Enzyme Link: | BRENDA 1.13.11.45 |
KEGG Enzyme Link: | KEGG1.13.11.45 |
BioCyc Enzyme Link: | BioCyc 1.13.11.45 |
ExPASy Enzyme Link: | ExPASy1.13.11.45 |
EC2PDB Enzyme Link: | EC2PDB 1.13.11.45 |
ExplorEnz Enzyme Link: | ExplorEnz 1.13.11.45 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.13.11.45 |
IntEnz Enzyme Link: | IntEnz 1.13.11.45 |
MEDLINE Enzyme Link: | MEDLINE 1.13.11.45 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:18993 | (9Z,12Z)-octadecadienoate + O2 = (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate |
RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[O;H0;+0:4]=[O;H0;+0:5]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[OH;+0:5] |
Reaction | ![]() |
Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
Title | Authors | Date | PubMed ID |
---|---|---|---|
Analysis of novel hydroperoxides and other metabolites of oleic, linoleic, and linolenic acids by liquid chromatography-mass spectrometry with ion trap MSn. | Oliw EH, Su C, Skogström T, Benthin G | 1998 Sep | 9778131 |
Manganese lipoxygenase. Discovery of a bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction. | Hamberg M, Su C, Oliw E | 1998 May 22 | 9582346 |
Manganese lipoxygenase. Purification and characterization. | Su C, Oliw EH | 1998 May 22 | 9582345 |
Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid. | Wennman A, Jernerén F, Magnuson A, Oliw EH | 2015 Oct 1 | 26264916 |
Secretion of two novel enzymes, manganese 9S-lipoxygenase and epoxy alcohol synthase, by the rice pathogen Magnaporthe salvinii. | Wennman A, Oliw EH | 2013 Mar | 23233731 |