Enzyme

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EC Tree
     1. Oxidoreductases
        1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
            1.13.11 With incorporation of two atoms of oxygen
ID:1.13.11.45
Description:Linoleate 11-lipoxygenase.
Alternative Name: Manganese lipoxygenase.
Linoleate dioxygenase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.13.11.45
BRENDA Enzyme Link: BRENDA 1.13.11.45
KEGG Enzyme Link: KEGG1.13.11.45
BioCyc Enzyme Link: BioCyc 1.13.11.45
ExPASy Enzyme Link: ExPASy1.13.11.45
EC2PDB Enzyme Link: EC2PDB 1.13.11.45
ExplorEnz Enzyme Link: ExplorEnz 1.13.11.45
PRIAM enzyme-specific profiles Link: PRIAM 1.13.11.45
IntEnz Enzyme Link: IntEnz 1.13.11.45
MEDLINE Enzyme Link: MEDLINE 1.13.11.45
MSA:

1.13.11.45;

Phylogenetic Tree:

1.13.11.45;

Uniprot:
M-CSA:
RHEA:18993 (9Z,12Z)-octadecadienoate + O2 = (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[O;H0;+0:4]=[O;H0;+0:5]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[OH;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Analysis of novel hydroperoxides and other metabolites of oleic, linoleic, and linolenic acids by liquid chromatography-mass spectrometry with ion trap MSn.Oliw EH, Su C, Skogström T, Benthin G1998 Sep9778131
Manganese lipoxygenase. Discovery of a bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction.Hamberg M, Su C, Oliw E1998 May 229582346
Manganese lipoxygenase. Purification and characterization.Su C, Oliw EH1998 May 229582345
Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid.Wennman A, Jernerén F, Magnuson A, Oliw EH2015 Oct 126264916
Secretion of two novel enzymes, manganese 9S-lipoxygenase and epoxy alcohol synthase, by the rice pathogen Magnaporthe salvinii.Wennman A, Oliw EH2013 Mar23233731