| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.11 With incorporation of two atoms of oxygen |
| ID: | 1.13.11.45 |
|---|---|
| Description: | Linoleate 11-lipoxygenase. |
| Alternative Name: |
Manganese lipoxygenase. Linoleate dioxygenase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.13.11.45 |
| BRENDA Enzyme Link: | BRENDA 1.13.11.45 |
| KEGG Enzyme Link: | KEGG1.13.11.45 |
| BioCyc Enzyme Link: | BioCyc 1.13.11.45 |
| ExPASy Enzyme Link: | ExPASy1.13.11.45 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.11.45 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.11.45 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.11.45 |
| IntEnz Enzyme Link: | IntEnz 1.13.11.45 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.11.45 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:18993 | (9Z,12Z)-octadecadienoate + O2 = (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[O;H0;+0:4]=[O;H0;+0:5]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[OH;+0:5] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Analysis of novel hydroperoxides and other metabolites of oleic, linoleic, and linolenic acids by liquid chromatography-mass spectrometry with ion trap MSn. | Oliw EH, Su C, Skogström T, Benthin G | 1998 Sep | 9778131 |
| Manganese lipoxygenase. Discovery of a bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction. | Hamberg M, Su C, Oliw E | 1998 May 22 | 9582346 |
| Manganese lipoxygenase. Purification and characterization. | Su C, Oliw EH | 1998 May 22 | 9582345 |
| Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid. | Wennman A, Jernerén F, Magnuson A, Oliw EH | 2015 Oct 1 | 26264916 |
| Secretion of two novel enzymes, manganese 9S-lipoxygenase and epoxy alcohol synthase, by the rice pathogen Magnaporthe salvinii. | Wennman A, Oliw EH | 2013 Mar | 23233731 |