Enzyme

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EC Tree
     1. Oxidoreductases
        1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
            1.13.11 With incorporation of two atoms of oxygen
ID:1.13.11.46
Description:4-hydroxymandelate synthase.
Alternative Name: 4-hydroxyphenylpyruvate dioxygenase II.
Cath: 3.10.180.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.13.11.46
BRENDA Enzyme Link: BRENDA 1.13.11.46
KEGG Enzyme Link: KEGG1.13.11.46
BioCyc Enzyme Link: BioCyc 1.13.11.46
ExPASy Enzyme Link: ExPASy1.13.11.46
EC2PDB Enzyme Link: EC2PDB 1.13.11.46
ExplorEnz Enzyme Link: ExplorEnz 1.13.11.46
PRIAM enzyme-specific profiles Link: PRIAM 1.13.11.46
IntEnz Enzyme Link: IntEnz 1.13.11.46
MEDLINE Enzyme Link: MEDLINE 1.13.11.46
MSA:

1.13.11.46;

Phylogenetic Tree:

1.13.11.46;

Uniprot:
M-CSA:
RHEA:21376 3-(4-hydroxyphenyl)pyruvate + O2 = (S)-4-hydroxymandelate + CO2
RULE(radius=1) [*:1]=[C;H0;+0:2](-[OH;+0:3])-[C;H0;+0:4](=[*:5])-[CH2;+0:6]-[*:7].[O;H0;+0:8]=[O;H0;+0:9]>>[*:5]=[C;H0;+0:4](-[OH;+0:8])-[CH;+0:6](-[*:7])-[OH;+0:9].[*:1]=[C;H0;+0:2]=[O;H0;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics.Hubbard BK, Thomas MG, Walsh CT2000 Dec11137816