| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.11 With incorporation of two atoms of oxygen |
| ID: | 1.13.11.46 |
|---|---|
| Description: | 4-hydroxymandelate synthase. |
| Alternative Name: |
4-hydroxyphenylpyruvate dioxygenase II. |
| Cath: | 3.10.180.10; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.13.11.46 |
| BRENDA Enzyme Link: | BRENDA 1.13.11.46 |
| KEGG Enzyme Link: | KEGG1.13.11.46 |
| BioCyc Enzyme Link: | BioCyc 1.13.11.46 |
| ExPASy Enzyme Link: | ExPASy1.13.11.46 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.11.46 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.11.46 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.11.46 |
| IntEnz Enzyme Link: | IntEnz 1.13.11.46 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.11.46 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:21376 | 3-(4-hydroxyphenyl)pyruvate + O2 = (S)-4-hydroxymandelate + CO2 |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[C;H0;+0:4](=[*:5])-[CH2;+0:6]-[*:7].[O;H0;+0:8]=[O;H0;+0:9]>>[*:5]=[C;H0;+0:4](-[OH;+0:8])-[CH;+0:6](-[*:7])-[OH;+0:9].[*:1]=[C;H0;+0:2]=[O;H0;+0:3] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics. | Hubbard BK, Thomas MG, Walsh CT | 2000 Dec | 11137816 |