EC number:1.13.11.5

Enzyme

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EC Tree
     1. Oxidoreductases
        1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
            1.13.11 With incorporation of two atoms of oxygen
ID:1.13.11.5
Description:Homogentisate 1,2-dioxygenase.
Alternative Name: Homogentisicase.
Homogentisic acid oxidase.
Homogentisate oxygenase.
Cath: 2.60.120.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.13.11.5
BRENDA Enzyme Link: BRENDA 1.13.11.5
KEGG Enzyme Link: KEGG1.13.11.5
BioCyc Enzyme Link: BioCyc 1.13.11.5
ExPASy Enzyme Link: ExPASy1.13.11.5
EC2PDB Enzyme Link: EC2PDB 1.13.11.5
ExplorEnz Enzyme Link: ExplorEnz 1.13.11.5
PRIAM enzyme-specific profiles Link: PRIAM 1.13.11.5
IntEnz Enzyme Link: IntEnz 1.13.11.5
MEDLINE Enzyme Link: MEDLINE 1.13.11.5

EC number:1.13.11.5

MSA:

1.13.11.5;
Phylogenetic Tree:

1.13.11.5;
Uniprot:
M-CSA:
RHEA:15449 homogentisate + O2 = 4-maleylacetoacetate + H(+)
RULE(radius=1) [*:1]-[c;H0;+0:2]1:[cH;+0:3]:[c;H0;+0:4](-[OH;+0:5]):[cH;+0:6]:[cH;+0:7]:[c;H0;+0:8]:1-[OH;+0:9].[O;H0;+0:10]=[O;H0;+0:11]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:11])-[CH2;+0:3]-[C;H0;+0:4](=[O;H0;+0:5])-[CH;+0:6]=[CH;+0:7]-[C;H0;+0:8](=[O;H0;+0:9])-[OH;+0:10]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction