EC number:1.13.11.50

Enzyme

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     1. Oxidoreductases
        1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
            1.13.11 With incorporation of two atoms of oxygen
ID:1.13.11.50
Description:Acetylacetone-cleaving enzyme.
Alternative Name: Diketone cleaving enzyme.
Diketone cleaving dioxygenase.
Acetylacetone dioxygenase.
Cath: 2.60.120.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.13.11.50
BRENDA Enzyme Link: BRENDA 1.13.11.50
KEGG Enzyme Link: KEGG1.13.11.50
BioCyc Enzyme Link: BioCyc 1.13.11.50
ExPASy Enzyme Link: ExPASy1.13.11.50
EC2PDB Enzyme Link: EC2PDB 1.13.11.50
ExplorEnz Enzyme Link: ExplorEnz 1.13.11.50
PRIAM enzyme-specific profiles Link: PRIAM 1.13.11.50
IntEnz Enzyme Link: IntEnz 1.13.11.50
MEDLINE Enzyme Link: MEDLINE 1.13.11.50

EC number:1.13.11.50

MSA:

1.13.11.50;
Phylogenetic Tree:

1.13.11.50;
Uniprot:
M-CSA:
RHEA:12877 acetylacetone + O2 = acetate + H(+) + methylglyoxal
RULE(radius=1) [*:1]=[C;H0;+0:2](-[*:3])-[CH2;+0:4]-[*:5].[O;H0;+0:6]=[O;H0;+0:7]>>[*:5]-[CH;+0:4]=[O;H0;+0:6].[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Emergent mechanistic diversity of enzyme-catalysed beta-diketone cleavage.Grogan G2005 Jun 1515934927
Acetylacetone-cleaving enzyme Dke1: a novel C-C-bond-cleaving enzyme from Acinetobacter johnsonii.Straganz GD, Glieder A, Brecker L, Ribbons DW, Steiner W2003 Feb 112379146