| EC Tree |
| 1. Oxidoreductases |
| 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) |
| 1.13.11 With incorporation of two atoms of oxygen |
| ID: | 1.13.11.51 |
|---|---|
| Description: | 9-cis-epoxycarotenoid dioxygenase. |
| Alternative Name: |
VP14. Nine-cis-epoxycarotenoid dioxygenase. NCED. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.13.11.51 |
| BRENDA Enzyme Link: | BRENDA 1.13.11.51 |
| KEGG Enzyme Link: | KEGG1.13.11.51 |
| BioCyc Enzyme Link: | BioCyc 1.13.11.51 |
| ExPASy Enzyme Link: | ExPASy1.13.11.51 |
| EC2PDB Enzyme Link: | EC2PDB 1.13.11.51 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.13.11.51 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.13.11.51 |
| IntEnz Enzyme Link: | IntEnz 1.13.11.51 |
| MEDLINE Enzyme Link: | MEDLINE 1.13.11.51 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:16541 | 9-cis-violaxanthin + O2 = (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al + 2-cis,4-trans-xanthoxin |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[O;H0;+0:5]=[O;H0;+0:6]>>[*:1]-[CH;+0:2]=[O;H0;+0:5].[*:4]-[CH;+0:3]=[O;H0;+0:6] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Genetic control of abscisic acid biosynthesis in maize. | Tan BC, Schwartz SH, Zeevaart JA, McCarty DR | 1997 Oct 28 | 9342392 |
| Specific oxidative cleavage of carotenoids by VP14 of maize. | Schwartz SH, Tan BC, Gage DA, Zeevaart JA, McCarty DR | 1997 Jun 20 | 9188535 |
| Regulation of drought tolerance by gene manipulation of 9-cis-epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis. | Iuchi S, Kobayashi M, Taji T, Naramoto M, Seki M, Kato T, Tabata S, Kakubari Y, Yamaguchi-Shinozaki K, Shinozaki K | 2001 Aug | 11532178 |
| Ectopic expression of a tomato 9-cis-epoxycarotenoid dioxygenase gene causes over-production of abscisic acid. | Thompson AJ, Jackson AC, Symonds RC, Mulholland BJ, Dadswell AR, Blake PS, Burbidge A, Taylor IB | 2000 Aug | 10929129 |
| The 9-cis-epoxycarotenoid cleavage reaction is the key regulatory step of abscisic acid biosynthesis in water-stressed bean. | Qin X, Zeevaart JA | 1999 Dec 21 | 10611388 |
| RHEA:19677 | 9'-cis-neoxanthin + O2 = (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al + 2-cis,4-trans-xanthoxin |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[O;H0;+0:5]=[O;H0;+0:6]>>[*:1]-[CH;+0:2]=[O;H0;+0:5].[*:4]-[CH;+0:3]=[O;H0;+0:6] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Genetic control of abscisic acid biosynthesis in maize. | Tan BC, Schwartz SH, Zeevaart JA, McCarty DR | 1997 Oct 28 | 9342392 |
| Specific oxidative cleavage of carotenoids by VP14 of maize. | Schwartz SH, Tan BC, Gage DA, Zeevaart JA, McCarty DR | 1997 Jun 20 | 9188535 |
| Regulation of drought tolerance by gene manipulation of 9-cis-epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis. | Iuchi S, Kobayashi M, Taji T, Naramoto M, Seki M, Kato T, Tabata S, Kakubari Y, Yamaguchi-Shinozaki K, Shinozaki K | 2001 Aug | 11532178 |
| Ectopic expression of a tomato 9-cis-epoxycarotenoid dioxygenase gene causes over-production of abscisic acid. | Thompson AJ, Jackson AC, Symonds RC, Mulholland BJ, Dadswell AR, Blake PS, Burbidge A, Taylor IB | 2000 Aug | 10929129 |
| The 9-cis-epoxycarotenoid cleavage reaction is the key regulatory step of abscisic acid biosynthesis in water-stressed bean. | Qin X, Zeevaart JA | 1999 Dec 21 | 10611388 |
| RHEA:23328 | a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[O;H0;+0:5]=[O;H0;+0:6]>>[*:4]-[CH;+0:3]=[O;H0;+0:5].[*:1]-[CH;+0:2]=[O;H0;+0:6] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Genetic control of abscisic acid biosynthesis in maize. | Tan BC, Schwartz SH, Zeevaart JA, McCarty DR | 1997 Oct 28 | 9342392 |
| Specific oxidative cleavage of carotenoids by VP14 of maize. | Schwartz SH, Tan BC, Gage DA, Zeevaart JA, McCarty DR | 1997 Jun 20 | 9188535 |
| Regulation of drought tolerance by gene manipulation of 9-cis-epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis. | Iuchi S, Kobayashi M, Taji T, Naramoto M, Seki M, Kato T, Tabata S, Kakubari Y, Yamaguchi-Shinozaki K, Shinozaki K | 2001 Aug | 11532178 |
| Ectopic expression of a tomato 9-cis-epoxycarotenoid dioxygenase gene causes over-production of abscisic acid. | Thompson AJ, Jackson AC, Symonds RC, Mulholland BJ, Dadswell AR, Blake PS, Burbidge A, Taylor IB | 2000 Aug | 10929129 |
| The 9-cis-epoxycarotenoid cleavage reaction is the key regulatory step of abscisic acid biosynthesis in water-stressed bean. | Qin X, Zeevaart JA | 1999 Dec 21 | 10611388 |